Ficus simplicissima is a species of fig tree native to parts of Asia, including Vietnam, China, and the Himalayas. In some traditional medicinal systems, particularly in Vietnam and neighboring regions, various parts of the plant (such as leaves, latex, or bark) have been used to address a range of ailments, including chest pain. The traditional use of Ficus simplicissima for chest pain is mostly rooted in folk medicine, where it is believed to possess anti-inflammatory, analgesic, or tonic properties that could alleviate discomfort or pain in the chest area. However, these uses are largely based on anecdotal evidence and ethnobotanical surveys rather than rigorous clinical studies.

Scientific literature on Ficus simplicissima is limited, and there are no published clinical trials or pharmacological studies directly supporting its efficacy for treating chest pain (which can be a symptom of many underlying conditions). Some studies have identified general antioxidant and anti-inflammatory compounds in related Ficus species, but this does not equate to validated therapeutic use for chest pain, especially of cardiac origin. Overall, the use of Ficus simplicissima for chest pain is primarily justified by tradition, with minimal evidence rating due to the lack of robust scientific validation.