Evidence supporting the use of: Goldthread (unspecified)
For the health condition: Chest Pain

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Goldthread, referring to plants in the Coptis genus (such as Coptis chinensis), has a long history of use in traditional Chinese medicine (TCM). It is mainly valued for its bitter, cooling properties and is traditionally used to "clear heat" and "dry dampness," primarily in the context of digestive complaints, infections, and inflammation. Occasionally, in classical TCM texts, Goldthread is included in formulas addressing "chest impediment" or "chest pain" (referred to as "xiong bi"), but this is generally in the context of syndromes attributed to internal heat toxins or damp-heat obstructing the chest. The main active constituent, berberine, does have a range of pharmacological actions, including antimicrobial, anti-inflammatory, and some cardiovascular effects. However, there is no robust modern clinical evidence supporting Goldthread’s effectiveness specifically for chest pain—either angina, musculoskeletal pain, or other etiologies. Its use for this purpose remains based on traditional theory rather than empirical validation. No major clinical guidelines or modern herbal pharmacopeias recommend Goldthread for chest pain as a primary indication. Thus, while there is some historical precedent, the evidence supporting its use for chest pain is weak and cannot be considered scientifically validated.

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