Evidence supporting the use of: Oxygen
For the health condition: Chest Pain

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Oxygen therapy has traditionally been used to treat chest pain, especially in the context of suspected acute coronary syndromes (ACS) such as myocardial infarction (MI). The rationale historically was that supplemental oxygen would increase oxygen delivery to ischemic heart tissue, potentially limiting infarct size and improving outcomes. However, recent large-scale clinical trials and systematic reviews have questioned the universal benefit of routine oxygen administration in all patients with chest pain or suspected ACS. For patients who are hypoxemic (typically defined as oxygen saturation <90–94%), supplemental oxygen is scientifically validated and recommended to correct hypoxemia and prevent complications from inadequate tissue oxygenation. For non-hypoxemic patients (normal oxygen saturation), evidence from trials such as the AVOID and DETO2X-AMI studies has shown no significant benefit, and some data suggest possible harm from unnecessary oxygen supplementation, such as increased risk of hyperoxia-induced vasoconstriction and oxidative stress. As a result, current guidelines (e.g., from the American Heart Association and European Society of Cardiology) recommend oxygen only for patients with chest pain who are hypoxemic or in respiratory distress. In summary, while the use of oxygen in hypoxemic chest pain patients is scientifically supported, routine use in normoxic patients is not supported by strong evidence, leading to a moderate evidence rating.

More about Oxygen
More about Chest Pain

Products containing Oxygen

We currently have no products on Vitabase that contain this ingredient.