Evidence supporting the use of: Solanaceae
For the health condition: Chest Pain

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

The use of unspecified Solanaceae plants (the nightshade family, which includes species such as Atropa belladonna, Datura spp., and Capsicum spp.) for chest pain is primarily rooted in traditional medicine practices rather than robust scientific validation. Historically, certain Solanaceae plants like Atropa belladonna and Datura have been used in various cultures for their anticholinergic and analgesic properties, sometimes being applied to relieve pain, including chest pain, muscle spasms, and other discomforts. The rationale was often based on the presence of alkaloids such as atropine and scopolamine, which can have muscle-relaxant and pain-relieving effects, albeit with significant toxicity risks.

However, the use of Solanaceae for chest pain is poorly documented in contemporary clinical literature, and there is a lack of high-quality evidence (randomized controlled trials or systematic reviews) supporting their safe or effective use for this indication. Most uses are anecdotal, drawn from ethnobotanical reports or historical texts. In modern medicine, due to potential toxicity (delirium, tachycardia, respiratory depression), these plants are not recommended for self-treatment of chest pain, which is often a sign of serious cardiovascular conditions requiring immediate medical attention. Any analgesic effects are overshadowed by the danger of misuse. Therefore, while traditional use is documented, scientific support is minimal, and the evidence is weak.

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