Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Caesalpinia crista, also known as fever nut or Karanjwa, has a long history of use in traditional medicine systems such as Ayurveda and Unani for the management of fever and chills. In these traditions, chills are often associated with intermittent fevers, such as those seen in malaria. The seeds and sometimes the leaves of Caesalpinia crista are used for their purported antipyretic (fever-reducing) and tonic properties. Ancient Ayurvedic texts describe the use of this plant’s seeds in formulations (like Sudarshan Churna) to “break” fevers and relieve associated chills and rigors.

The rationale for its use is mostly based on empirical and anecdotal evidence accumulated over centuries, rather than systematic scientific studies. Some phytochemical analyses have identified alkaloids, flavonoids, and diterpenes in Caesalpinia crista that possess potential antimicrobial and antipyretic activity, but robust clinical trials in humans are lacking. A few in vivo animal studies suggest antipyretic effects, but these findings are preliminary and not specific to the symptom of chills.

Overall, the use of Caesalpinia crista for chills is justified primarily by its traditional application as a fever remedy. While there is some experimental support for its antipyretic properties, the evidence is not strong or specific enough to confirm efficacy for chills according to modern scientific standards.

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