Evidence supporting the use of: Isatis
For the health condition: Chills

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Isatis, particularly the root (Isatis tinctoria, also known as Ban Lan Gen in Traditional Chinese Medicine or TCM), is traditionally used in TCM to "clear heat" and "remove toxins." It is primarily used for sore throat, fever, and various infectious diseases, but not specifically or directly for "chills" as an isolated symptom. However, in TCM theory, chills are often considered a manifestation of "wind-cold" or early-stage external pathogenic invasion, and Isatis is sometimes included in complex herbal formulas aimed at treating such conditions. The rationale is that by clearing heat and supporting the body's defenses, Isatis might help with symptoms associated with the initial stages of an infection, which can include chills. There is limited scientific evidence directly supporting the use of Isatis for chills. Most studies and reviews focus on its antiviral, antibacterial, and anti-inflammatory properties, and some clinical trials have evaluated its effect on respiratory infections, influenza, and fever reduction. However, these studies generally do not isolate "chills" as a specific outcome measure. Therefore, its use for chills is primarily rooted in traditional practice, with indirect scientific support related to its general anti-infective and antipyretic activities. The overall evidence for this specific use is weak to moderate (2/5), largely based on historical context rather than robust clinical data.

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