Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Neem (Azadirachta indica) has been used in traditional medicine systems such as Ayurveda and Unani primarily for its antipyretic (fever-reducing) and anti-inflammatory properties. The use of the neem tree to support or treat chills appears to be linked to its broader traditional use in managing fevers and infections, as chills often accompany febrile illnesses. In classical Ayurvedic texts, neem leaves and their preparations are recommended for reducing fever, purifying the blood, and combating various infections. The rationale is that by addressing the underlying infection or fever, the associated chills may also resolve. However, direct references to neem specifically for the treatment of chills (as opposed to fever) are not prominent in traditional texts.

From a scientific perspective, neem contains compounds such as nimbin, nimbidin, and azadirachtin, which have demonstrated antimicrobial, anti-inflammatory, and antipyretic activities in laboratory studies. Some animal studies suggest neem extracts can reduce fever, supporting its traditional antipyretic use. Nonetheless, there is limited direct clinical evidence specifically evaluating neem's efficacy for chills, as most research focuses on its general antipyretic and antimicrobial properties. Therefore, while traditional practices justify neem's application for fevers (and by association, chills), robust scientific validation for its direct use for chills is lacking, resulting in a moderate evidence rating.

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