Evidence supporting the use of: Cynanchum (unspecified)
For the health condition: Cholera

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Cynanchum, a genus of plants in the Apocynaceae family, has a history of use in traditional medicine across various cultures, particularly in Asia. Some species, such as Cynanchum atratum and Cynanchum paniculatum, are mentioned in historical Chinese and Korean medical texts for their purported abilities to "clear heat" and "detoxify," which, in traditional frameworks, could relate to treating symptoms of infectious diseases like cholera. However, the references are often broad and do not specifically equate to modern cholera (caused by Vibrio cholerae), but rather to severe diarrheal illnesses in general. There is minimal direct scientific investigation into the efficacy of Cynanchum extracts against cholera bacteria or cholera toxin, and no modern clinical trials substantiate its use for this condition. Most available information points to its inclusion in traditional herbal formulas aimed at treating diarrhea and dysentery, possibly due to anecdotal observations or empirical use over centuries. Therefore, while there is a basis in tradition for its use in diarrheal diseases that may have included cholera-like illnesses, the evidence is limited, and scientific validation is lacking.

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