Evidence supporting the use of: Melia
For the health condition: Cholera

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

The use of Melia species (most commonly Melia azedarach, also known as Chinaberry or Persian Lilac) to support or treat cholera is primarily rooted in traditional medicine systems, especially in South Asia and parts of Africa. Historical ethnobotanical records indicate that various parts of the Melia tree—such as bark, leaves, and seeds—have been used in folk remedies for gastrointestinal complaints, including diarrhea and dysentery, which are symptoms associated with cholera. Some traditional healers have employed decoctions or extracts in attempts to relieve symptoms or as general antimicrobial agents. However, there is a lack of robust clinical or preclinical evidence specifically validating Melia's efficacy against Vibrio cholerae or cholera in controlled scientific studies. The limited scientific literature that exists focuses on potential antimicrobial or antiparasitic properties in vitro, but these findings are preliminary and do not directly address cholera or its treatment in humans. Furthermore, Melia species can be toxic, and adverse effects have been reported with improper use. In summary, while Melia has a history of traditional use for diarrheal diseases, there is minimal scientific support for its use specifically in cholera, and safety concerns further limit its applicability.

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