Evidence supporting the use of: Morinda
For the health condition: Cholera

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Morinda, particularly Morinda citrifolia (commonly known as noni), has a long history of use in traditional medicine systems across South and Southeast Asia, as well as the Pacific Islands. In traditional Ayurvedic and folk medicine, various parts of the morinda plant—especially the fruit and root—have been used to treat digestive ailments, including diarrhea and dysentery, which are symptoms associated with cholera. Ancient texts and ethnobotanical reports mention the use of morinda for "looseness of bowels" and gastrointestinal disturbances, suggesting its application in cases resembling cholera. The rationale in traditional medicine is often based on the plant's perceived antimicrobial and astringent properties.

However, scientific studies directly validating morinda’s effectiveness against Vibrio cholerae, the bacterium responsible for cholera, are limited. Some in vitro studies have shown that extracts of Morinda citrifolia possess antibacterial activity against a range of pathogens, including certain Gram-negative bacteria, but robust clinical trials or direct evidence for its use in cholera treatment are lacking. Thus, the primary justification for its use comes from traditional practice, not from rigorous scientific validation. Modern clinical management of cholera still relies on oral rehydration therapy and antibiotics, not herbal remedies. Therefore, while morinda is traditionally used for symptoms overlapping with cholera, the scientific evidence supporting its efficacy is weak.

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