Evidence supporting the use of: Oxystelma
For the health condition: Cholera

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Oxystelma, particularly Oxystelma esculentum, is referenced in various traditional medical systems, especially in Ayurveda and some local folk medicines, as a remedy for gastrointestinal complaints, including diarrhea and cholera-like symptoms. Historical texts and ethnobotanical surveys document its use as an anti-diarrheal or for "purifying" the digestive system. However, the basis for this use is largely empirical and rooted in traditional practices rather than in modern scientific validation. There are very limited, if any, peer-reviewed pharmacological studies specifically investigating the efficacy of Oxystelma in treating cholera or its causative agent, Vibrio cholerae. Most available references cite its use in broader terms, such as for stomach ailments or as a general tonic, rather than for cholera specifically. Consequently, while its traditional use is documented, the quality and specificity of evidence are low, and there is a lack of clinical or preclinical studies supporting its effectiveness against cholera. Therefore, Oxystelma’s use for cholera should be considered as primarily traditional, with weak supporting evidence and no robust scientific validation as of the current literature.

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