Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Rice, specifically in the form of rice-based oral rehydration solution (ORS), has a strong scientific basis for its use in the treatment of cholera. Cholera is characterized by severe diarrhea leading to rapid dehydration, and the cornerstone of treatment is prompt and effective rehydration. Traditional glucose-based ORS is widely used, but scientific studies have shown that rice-based ORS can be superior in some cases, especially in the management of cholera-induced diarrhea.

The mechanism involves the sodium-glucose co-transport system in the intestines, which is also stimulated by rice starch. When rice powder is used instead of glucose in ORS, it is hydrolyzed into simple sugars more slowly, resulting in enhanced water and sodium absorption and reduced stool output. Clinical trials, particularly in cholera patients, have demonstrated that rice-based ORS can reduce the volume and duration of diarrhea more effectively than standard glucose-based ORS, especially in adults.

The World Health Organization and UNICEF acknowledge rice-based ORS as a viable alternative, particularly in regions where rice is readily available and culturally accepted. This approach is supported by multiple randomized controlled trials and systematic reviews. While glucose-based ORS remains the standard worldwide, rice-based ORS represents a scientifically validated, culturally adaptable, and often cost-effective option in the management of cholera.

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