Evidence supporting the use of: Sickle-leaf hare's ear
For the health condition: Cholera

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Sickle-leaf hare's ear (Bupleurum falcatum) is primarily used in traditional herbal medicine, particularly within Chinese and some other Asian medical systems. Historical texts and ethnobotanical records indicate that species of Bupleurum have been employed for ailments involving fever, inflammation, and gastrointestinal disturbances. In the context of cholera, traditional healers may have employed sickle-leaf hare’s ear or related species in decoctions or formulas aimed at supporting the digestive system, reducing fever, or managing symptoms such as diarrhea and vomiting. However, there is minimal scientific literature or clinical evidence directly supporting its efficacy against cholera or its causative agent, Vibrio cholerae. The use of Bupleurum for cholera is not a common feature in modern herbal pharmacopeias, and most references are anecdotal or based on broader uses for digestive complaints or infectious diseases. While the plant contains compounds with anti-inflammatory and possible hepatoprotective effects, no robust clinical trials or pharmacological studies have validated its use specifically for cholera. Therefore, the evidence supporting sickle-leaf hare’s ear for cholera is primarily traditional and rated low in strength.

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