Evidence supporting the use of: Trichosanthis
For the health condition: Cholera

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Trichosanthis, particularly the species Trichosanthes kirilowii or Trichosanthes cucumerina, is included in traditional herbal medicine systems such as Traditional Chinese Medicine (TCM) and Ayurveda. In these traditions, various parts of the plant—roots, seeds, and fruit—have been used to treat a range of conditions, including fevers, cough, constipation, and sometimes infectious diseases. Historical texts occasionally list Trichosanthis as a remedy for symptoms resembling those of cholera, such as severe diarrhea and dehydration, based on its perceived cooling and detoxifying properties. However, these uses are based on empirical tradition rather than controlled scientific studies.

The evidence supporting Trichosanthis for cholera is extremely limited. There are no modern clinical trials or robust pharmacological studies demonstrating efficacy against Vibrio cholerae infection or its symptoms. Most references to its use in cholera are anecdotal or derived from historic materia medica compilations. Therefore, while its use is justified by tradition, the evidence base is weak, and it is not recommended as a substitute for established medical treatments for cholera, such as oral rehydration therapy and antibiotics.

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