Evidence supporting the use of: Ginseng
For the health condition: Cholesterol (high)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ginseng has been explored for its potential effects on cholesterol levels, with both traditional and scientific interest. Traditionally, ginseng has been used in East Asian medicine for a variety of health conditions, including promoting general cardiovascular health. In recent decades, scientific studies—primarily using Panax ginseng (Asian ginseng) and Panax quinquefolius (American ginseng)—have examined its impact on lipid profiles. Some randomized controlled trials and meta-analyses have reported modest reductions in total cholesterol, LDL ("bad" cholesterol), and triglycerides with ginseng supplementation, while others have shown little to no effect.

Mechanistically, ginsenosides (the active compounds in ginseng) may influence hepatic cholesterol metabolism, reduce intestinal absorption of cholesterol, and improve antioxidant and anti-inflammatory status, which collectively could have favorable effects on lipid profiles. However, the overall quality and size of existing studies are limited, with variable formulations, dosages, and durations making direct comparisons difficult. Systematic reviews generally conclude that the lipid-lowering effect of ginseng is small and not always statistically significant.

In summary, while there is some scientific evidence suggesting ginseng may help lower cholesterol, the effect appears modest and inconsistent. Ginseng should not be relied upon as a primary therapy for high cholesterol, but may be considered as a complementary approach alongside established treatments, pending medical supervision.

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