Relationship: Cholesterol (high) and lycopene

Evidence supporting the use of: Lycopene
For the health condition: Cholesterol (high)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lycopene, a carotenoid pigment predominantly found in tomatoes and other red fruits, has attracted scientific interest for its potential cardiovascular benefits, including its effects on cholesterol levels. Several clinical studies and meta-analyses suggest that lycopene supplementation or increased dietary intake may modestly reduce total cholesterol and LDL cholesterol ("bad" cholesterol) in humans. The proposed mechanisms include its antioxidant properties, which may inhibit the oxidation of LDL cholesterol—a key step in the development of atherosclerosis. Additionally, lycopene may influence cholesterol metabolism directly by affecting enzymes involved in its synthesis and breakdown.

A 2011 meta-analysis published in "Maturitas" reviewed randomized controlled trials and found that lycopene supplementation (particularly at doses >25 mg/day) was associated with significant reductions in LDL cholesterol compared to controls. Other studies have corroborated these findings, although the magnitude of the effect is generally modest and may not be clinically significant for everyone. The evidence base is stronger for lycopene-rich diets (such as those high in tomatoes) rather than isolated supplements.

While lycopene has not traditionally been used specifically for cholesterol management, the modern scientific evidence supports a role for lycopene—primarily through dietary intake—in supporting healthy cholesterol levels. However, it should not be considered a substitute for established medical therapies. Overall, the evidence is moderate (rated 3/5), with further research needed to clarify optimal dosages and long-term effects.

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Other health conditions supported by lycopene

Alzheimer's Disease
Benign Prostate Hyperplasia
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cervical Dysplasia
Cholesterol (high)
Diabetes
Diabetic Retinopathy
Hypertension
Prostatitis
Triglycerides (high)
Wrinkles

Products containing lycopene

Health Concerns

Brands

Evidence supporting the use of: Lycopene
For the health condition: Cholesterol (high)

Table of Contents

Synopsis

Other ingredients used for Cholesterol (high)

Other health conditions supported by lycopene

Products containing lycopene

Health Concerns

Brands

Evidence supporting the use of: LycopeneFor the health condition: Cholesterol (high)

Table of Contents

Synopsis

Other ingredients used for Cholesterol (high)

Other health conditions supported by lycopene

Products containing lycopene

Evidence supporting the use of: Lycopene
For the health condition: Cholesterol (high)