Evidence supporting the use of: Polygonum
For the health condition: Cholesterol (high)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Polygonum species, particularly Polygonum multiflorum (also known as He Shou Wu or Fo-Ti), have a long history of use in traditional Chinese medicine for a variety of health conditions, including support for cardiovascular health. Traditional texts and herbal compendia often cite its use for "nourishing the blood," "strengthening the liver and kidneys," and promoting "longevity," which are sometimes interpreted as supportive of healthy cholesterol metabolism. There are anecdotal reports and historical records indicating its traditional employment for managing symptoms associated with hyperlipidemia (high cholesterol), though the condition itself was not defined as such in ancient times.

Modern scientific evidence for Polygonum's efficacy in lowering cholesterol is limited and primarily based on preclinical studies. Some animal studies and in vitro experiments suggest that extracts of P. multiflorum may have lipid-lowering effects, such as reducing total cholesterol, LDL cholesterol, and triglyceride levels. However, robust clinical trials in humans are lacking, and most evidence remains preliminary or indirect. Other Polygonum species (e.g., P. aviculare or P. cuspidatum) are less commonly referenced for cholesterol management in either traditional or scientific literature. Therefore, while traditional use is established, scientific validation remains weak, justifying a low evidence rating.

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Products containing Polygonum

We currently have no products on Vitabase that contain this ingredient.