Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Pomegranate (Punica granatum) has been investigated for its potential effects on cholesterol levels, particularly due to its rich content of polyphenols and antioxidants. Several clinical studies and animal models have explored its impact on lipid profiles, with a focus on its ability to reduce LDL cholesterol and potentially raise HDL cholesterol. For example, a randomized double-blind trial published in Clinical Nutrition (2014) found that pomegranate juice consumption over 8 weeks significantly reduced total cholesterol and LDL cholesterol in patients with type 2 diabetes. Another study in Atherosclerosis (2004) reported reduced LDL oxidation after pomegranate juice intake, which is relevant because oxidized LDL contributes to atherosclerosis risk. However, it is important to note that the majority of studies investigate the effect of pomegranate on high cholesterol (hypercholesterolemia), aiming to lower elevated cholesterol levels. There is little to no evidence supporting the use of pomegranate to increase cholesterol in individuals with low cholesterol (hypocholesterolemia). In fact, the existing research suggests that pomegranate is more likely to reduce cholesterol rather than support low cholesterol. In summary, there is moderate-quality scientific evidence supporting the use of pomegranate to help lower elevated cholesterol, but no evidence for its effectiveness in treating or supporting low cholesterol levels. Use of pomegranate for "cholesterol (low)" is not supported by current scientific literature.

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