Evidence supporting the use of: Carotenoids
For the health condition: Chronic Obstructive Pulmonary Disorder

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Carotenoids are naturally occurring pigments found in fruits and vegetables, with antioxidant properties that have been investigated for their role in supporting lung health, including in Chronic Obstructive Pulmonary Disease (COPD). Several observational studies have found that higher dietary intake or blood levels of carotenoids (such as beta-carotene, lycopene, and lutein) are associated with better lung function and a lower risk of developing COPD. The presumed mechanism involves the antioxidant and anti-inflammatory effects of carotenoids, which may help counteract the oxidative stress and inflammation that contribute to COPD pathology.

However, despite observational correlations, interventional trials supplementing carotenoids have yielded inconsistent results. There is insufficient robust clinical trial data to conclusively demonstrate that carotenoid supplementation improves COPD symptoms, slows disease progression, or reduces exacerbations. Some studies even raised concerns about high-dose beta-carotene supplementation, particularly in smokers, due to a potential increased risk of lung cancer. Current clinical guidelines do not recommend carotenoid supplements specifically for COPD management, though a diet rich in fruits and vegetables is encouraged for general health.

In summary, while there is some scientific interest and moderate observational evidence linking carotenoids to better lung health, the direct evidence for their therapeutic use in COPD is limited and does not yet support routine supplementation. The overall evidence rating is 2 out of 5.

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Products containing carotenoids

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