Evidence supporting the use of: Oxygen
For the health condition: Chronic Obstructive Pulmonary Disorder

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Oxygen therapy is scientifically validated and widely used in the management of Chronic Obstructive Pulmonary Disease (COPD), particularly in patients with severe hypoxemia. Multiple large-scale clinical trials, such as the Nocturnal Oxygen Therapy Trial (NOTT) and the Medical Research Council (MRC) trial in the 1980s, established that long-term oxygen therapy (LTOT) significantly improves survival in COPD patients with chronic respiratory failure (PaO2 ≤ 55 mmHg or SaO2 ≤ 88%). These findings are reflected in current clinical guidelines, such as those from the Global Initiative for Chronic Obstructive Lung Disease (GOLD) and the American Thoracic Society, which recommend oxygen therapy for COPD patients meeting specific hypoxemia criteria.

Oxygen works by increasing the amount of oxygen available in the blood, alleviating tissue hypoxia, reducing the workload on the heart, and improving quality of life and exercise tolerance in hypoxemic patients. While supplemental oxygen is not indicated for all COPD patients—particularly those without significant hypoxemia—it is a cornerstone of care for those with advanced disease and low blood oxygen levels. The evidence base supporting oxygen therapy in COPD is strong, with decades of research and consistent outcomes in both survival and symptom management.

More about Oxygen
More about Chronic Obstructive Pulmonary Disorder

Products containing Oxygen

We currently have no products on Vitabase that contain this ingredient.