Evidence supporting the use of: Coenzyme Q10 (CoQ10)
For the health condition: Circulation (poor)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Coenzyme Q10 (CoQ10) is a naturally occurring antioxidant found in most human cells, where it plays a key role in mitochondrial energy production. Its use for supporting or treating poor circulation is based on both its physiological role and several clinical studies, though the evidence is moderate rather than robust. CoQ10 has been studied primarily in the context of cardiovascular health, particularly in conditions such as heart failure, hypertension, and endothelial dysfunction—all of which are related to circulatory health. Some studies suggest that CoQ10 supplementation can improve endothelial function, which is crucial for healthy blood flow, by enhancing nitric oxide availability and reducing oxidative stress in blood vessels. Meta-analyses have demonstrated modest improvements in blood pressure and vascular function with CoQ10 supplementation. However, direct evidence for its efficacy in treating "poor circulation" as a generalized condition is limited, as most research focuses on specific cardiovascular diseases. The conventional use of CoQ10 for circulation is therefore extrapolated from its effects on cardiovascular endpoints. While CoQ10 is generally well-tolerated and considered safe, more high-quality, targeted studies are needed to establish its effectiveness for poor circulation specifically. In summary, CoQ10’s use for circulation is scientifically plausible and supported by some clinical research, but the strength of evidence is moderate, meriting a rating of 2 out of 5.
More about coenzyme Q10 (CoQ10)
More about Circulation (poor)
Other ingredients used for Circulation (poor)
2-(nitrooxy)ethyl 2-amino-3-methylbutanoate3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Acetyl L-carnitine
Achyranthes
Adrenergic amines
Ajoene
algal oil
Allicin
Alliin
Allium tuberosum
alpha-linolenic acid (ALA)
alpha-lipoic acid
amino acids
AMP-activated protein kinase (AMPK)
Angelica
anthocyanidins
anthocyanins
anthocyanosides
antler
Aralia
arginine alpha ketoglutarate
Arginine aspartate
arginine creatine
Arginine nitrate
Arginine silicate
arjun tree
arjuna
arjunic acid
Aronia melanocarpa
ashitaba
ashwagandha
asparagus
astaxanthin
Asteraceae
astragaloside
astragalus
atractylodes
atractylone
Auricularia
Autumn elaeagnus
Bassia scoparia
bee products
beet
bergamot
berry
bilberry
bioflavonoids
biota seed
birch
bishop\'s weed
black cumin
black currant
black galingale
black garlic
black ginger
black pepper
black tea
blackboard tree
blueberry
Boerhavia diffusa
borneol
bromelain
Buckwheat
Buddha\'s hand
bupleurum falcatum
bur-reed
burdock
butcher's broom
Butea monosperma
Caesalpinia crista
caffeine
calycosin
capillary artemisia
capsaicin
capsaicinoids
capsicum
capsinoids
cardamom
carqueja
Carthamus
cat's claw
catecholamine
caterpillar mushroom
cayenne pepper
celery
Centella asiatica
Centella triterpenes
chen pi
cherry
chestnut
Chinese mountain ant
Chinese salvia root
Chinese silkvine
chocolate
chokeberry
cinnamaldehyde
Cinnamomum
cinnamon
cistanche
Citrus
citrus bioflavonoids
citrus sinensis (proprietary)
clove
coca
cocoa
Codonopsis
coenzyme Q10 (CoQ10)
cola nut
Coleus forskohlii
commiphora
cordyceps
costus
coumarin
cowherb
Curcuma
curcumen
curcumin
Curcuminoid
currant
cyanidin
d-alpha tocopherol
danshen
date
DHA (docosahexaenoic acid)
diallyl disulfide (DADS)
diallyl sulfide
diallyl trisulfide (DATS)
dioscorea
diosmetin
Diosmin
dismutase
dodder
dodeca-2E, 4E, 8Z, 10Z/tetraenoic acid isobutylamide
dong quai
dong quai root
Echium
eicosapentaenoic acid
eleuthero
elk antler
enzymes blend (proprietary)
EPA (eicosapentaenoic acid)
ephedrine
epicatechin
essential oil blend
Ethylenediaminetetraacetic acid (EDTA)
Eupolyphaga sinensis
European five-finger grass
evodiamine
Fagopyrum
fatty acids
fish oil
fish protein
flat-stem milk-vetch
flavanols
flavanones
flavans
flavoglycosides
flavones
flavonoids
flavonols
flavonones
flaxseed
fo-ti
forskolin
fruit
fruit and vegetable blend (proprietary)
fungus
ganoderma
garlic
garlic bulb
gastrodia
ginger
ginkgo biloba
ginkgo flavone glycoside
ginseng
Ginsenosides
Glycoside
goji berry
gooseberry
gotu kola
grape
green tea
greens blend (proprietary)
Gypenoside
hawthorn
hazelnut
heal-all
Herb Robert
herbal blend (proprietary)
hesperetin
hesperidin
hibiscus
horse chestnut
horseradish
Huang hua
hydroxytyrosol
Hygrophila
icariin
Ilex
Indian bael
Indian kinotree
Indian tinospora
inositol nicotinate
inula racemosa
iron
jiaogulan
knotweed
kola nut
kudzu
L-arginine
l-carnitine
L-citrulline
Ligusticum
Ligustrazin
lingzhi
long pepper
lovage
lumbrokinase
mace
magnesium
mandarin
maral root
Marine fat
Marine lipid
Mate
Mistletoe
Monacolin
Monounsaturated fat
Morinda
Moringa
Mountain Pepper
Mulberry
Mushroom
Mustard
mustard seed
Naringin
Nattokinase
Nettle
Niacin (vitamin B3)
Niacinamide (vitamin B3)
nicotinamide riboside
Nutmeg
Oleuropein
Oligomeric proanthocyanidins
olive
omega-3 fatty acids
onion
orange
Oxystelma
oyster mushroom
paeoniflorin
Pentacyclic triterpenoids
peony
Pepper
Phaeophyceae
Phenylpropanoids
Phthalides
pine bark
Piper chaba
Piper retrofractum
Piperine
Pistachio
policosanol
Polydatin
Polygonum
polyphenols
polyunsaturated fat
pomegranate
prickly ash
proanthocyanidins
procyanidin
procyanidol
Propionyl-L-Carnitine
Puerarin
punarnava
punicalagins
purslane
Pycnogenol
Pyrrosia
quercetin
reishi mushroom
resveratrol
rhizome
ribose
rockweed
Rosa roxburghii
rose hips
rosemary
Ruscogenins
Ruscus
rutin
Rutosides
S-allylcysteine
safflower oil
Salidroside
Salmon Oil
Salvianolic acid
saponins
sarsaparilla
Schisandrins
seaweed
Serrapeptase
sesame
Sete sangrias
shiitake mushroom
Shilajit
Shogaol
Sichuan Lovage
Sichuan pepper
Sickle-leaf hare's ear
siler root
smilax
Southern Tsangshu
Spatholobus
spinach
Sulfated polysaccharide
suma
Sumac
Sweet Orange alcohol
Szechuan lovage
Tanshinone
Taraxacum
Taxifolin
Taxillus chinensis
Tea
Terminalia
Theobromine
tocotrienols
Triphala
Triterpenes
Troxerutin
turmeric
ubiquinol
vegetable and fruit blend (proprietary)
vegetable blend (proprietary)
Vinburnine
Vincamine
vitamin B
vitamin E
Watercress
Watermelon
Withanolides
Wulinshen
Xanthone
Xanthophyll
Xantinol Nicotinate
Xylaria nigripes
Yerba mate
Yohimbe
Yohimbine
zanthoxylum
Zingerone
Zucchini
Other health conditions supported by coenzyme Q10 (CoQ10)
Aging (prevention)Alzheimer's Disease
Angina
Apathy
Arrhythmia
Arteriosclerosis
Athletic and Exercise Aids
Cancer Treatment (reducing side effects)
Cardiac Arrest
Cardiovascular Disease
Chemotherapy (reducing side effects)
Circulation (poor)
Congestive Heart Failure
Depression
Diabetes
Endurance (lack of)
Energy (lack of)
Exercise
Fatigue
Fibromyalgia Syndrome
Free Radical Damage
Heart (weakness)
Heart Fibrillation or Palpitations
Hypertension
Memory and Brain Function
Migraine
Multiple Sclerosis
Muscle Tone (lack of)
Muscular Dystrophy
Nerve Damage
Oral Surgery
Parkinson's Disease
Peripheral Neuropathy
Rheumatoid Arthritis
Tinnitus
Products containing coenzyme Q10 (CoQ10)
Pure Encapsulations
Athletic Nutrients
Douglas Laboratories
Citrus-Q10 ™
Douglas Laboratories
Co-Enzyme Q10 Softgel
Douglas Laboratories
Coenzyme Q-10 with Lipoic Acid
Douglas Laboratories
Coenzyme Q-10 with Lipoic Acid
Integrative Therapeutics
CoQ10
Integrative Therapeutics
COQ10 100 mg Tropical
Pure Encapsulations
CoQ10 120 mg
Pure Encapsulations
CoQ10 120 mg
Pure Encapsulations
CoQ10 120 mg
Integrative Therapeutics
COQ10 200 mg Chocolate 30 chew tabs
Pure Encapsulations
CoQ10 250 mg
Pure Encapsulations
CoQ10 30 mg
Pure Encapsulations
CoQ10 500 mg
Pure Encapsulations
CoQ10 60 mg
Pure Encapsulations
CoQ10 60 mg
Pure Encapsulations
CoQ10 60 mg
Pure Encapsulations
CoQ10 l-Carnitine Fumarate
Thorne
CoQ10 Q-Best 100
Metagenics
CoQ10 ST®-100 mg
Metagenics
CoQ10 ST-100 mg
Metagenics
CoQ10 ST-200 mg
Integrative Therapeutics
Detoxication Factors
Integrative Therapeutics
Detoxication Factors
Pure Encapsulations
Energize Plus™ Pure Pack
Pure Encapsulations
Hair/Skin/Nails Ultra
Thorne
Heart Health Complex Q-10 Plus
Integrative Therapeutics
K-PAX MitoNutrients
Vitabase
Life's Essentials Plus
Designs For Health
Mito-NR™
Pure Encapsulations
Mitochondria-ATP
Designs For Health
Mitochondrial NRG™
Pure Encapsulations
NeuroMood Pure Pack
Metagenics
NutraGems® CoQ10 300
Pure Encapsulations
O.N.E.™ Multivitamin
Pure Encapsulations
O.N.E.™ Multivitamin
Pure Encapsulations
O.N.E.™ Multivitamin
Thorne
Omega-3 w/ CoQ10
Thorne
Ovarian Care
Integrative Therapeutics
ProThrivers Wellness Flav Complex
Pure Encapsulations
PureGenomics® UltraMultivitamin
Designs For Health
Q-Evail® 100
Designs For Health
Q-Evail® 200
Pure Encapsulations
Q-Gel® (Hydrosoluble™ CoQ10) 100 mg
Thorne
Red Yeast Rice + CoQ10 Choleast
Pure Encapsulations
Renual
Pure Encapsulations
RevitalAge™ Nerve
Pure Encapsulations
RevitalAge™ Ultra
Designs For Health
RYR Synergy™
Pure Encapsulations
SR-CoQ10 with PQQ
Vitabase
Super Fat Burner
Pure Encapsulations
Ubiquinol-QH 100 mg
Pure Encapsulations
Ubiquinol-QH 200 mg
Pure Encapsulations
Ubiquinol VESIsorb®
Integrative Therapeutics
UBQH 100 mg
Douglas Laboratories
Ultra Preventive 50+ -EZ Swallow
Douglas Laboratories
Ultra Preventive One Daily
Pure Encapsulations
Ultra Pure Pack
Pure Encapsulations
UltraDetox 10-Day Pure Pack
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
UltraNutrient®
Metagenics
Wellness Essentials Brain Health Daily Packs
