Synopsis

Source of validity: Scientific
Rating (out of 5): 3

L-arginine is an amino acid that serves as a precursor to nitric oxide (NO), a molecule essential for vasodilation and healthy blood flow. Scientific interest in L-arginine’s role in supporting circulation stems from its ability to increase NO production, which relaxes blood vessels, thereby improving blood flow and reducing blood pressure. Several clinical studies have explored L-arginine supplementation in populations with endothelial dysfunction, peripheral artery disease (PAD), and hypertension. Some trials report modest improvements in blood flow, exercise tolerance, and symptoms in individuals with compromised circulation, particularly those with PAD or angina. However, the evidence is mixed: while short-term studies demonstrate improvements in vascular function, longer-term benefits and impacts on clinical outcomes (such as cardiovascular events) are less clear. The American Heart Association and similar bodies acknowledge L-arginine’s mechanism but do not universally recommend its supplementation due to inconsistent results and potential risks in certain populations (e.g., post-myocardial infarction patients). In summary, L-arginine is scientifically validated as a nitric oxide precursor that can support vasodilation and circulation, with moderate-quality evidence suggesting benefits in some circulatory conditions, though routine use is not broadly endorsed without medical supervision.

More about L-arginine
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Other ingredients used for Circulation (poor)

Other health conditions supported by L-arginine

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