Evidence supporting the use of: Rutin
For the health condition: Circulation (poor)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Rutin is a flavonoid glycoside found in various plants, including buckwheat, citrus fruits, and apples. It has been traditionally used and scientifically investigated for its potential to support vascular health and improve poor circulation. Scientifically, rutin is known for its ability to strengthen capillaries, reduce capillary permeability, and act as an antioxidant. Several clinical and preclinical studies have explored its effects on venous disorders, such as chronic venous insufficiency, varicose veins, and hemorrhoids, conditions often related to poor circulation.

The evidence supporting rutin’s use in circulation primarily comes from studies demonstrating its ability to reduce symptoms like leg swelling, heaviness, and pain associated with venous insufficiency. Rutosides (a group of compounds including rutin) are included in some European guidelines for the symptomatic treatment of chronic venous disorders. The proposed mechanisms include reducing inflammation, decreasing oxidative stress, and stabilizing vascular walls. However, while there are positive findings, the overall quality and size of clinical trials are moderate, and more large-scale, high-quality research is needed for definitive conclusions.

In summary, rutin’s use for poor circulation is supported by both traditional usage and scientific research, with moderate evidence for efficacy, particularly in mild to moderate venous disorders. It is generally considered safe, though individuals should consult healthcare providers before starting supplementation, especially if taking other medications affecting blood flow or clotting.

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Achyranthes
Adrenergic amines
Ajoene
algal oil
Allicin
Alliin
Allium tuberosum
alpha-linolenic acid (ALA)
alpha-lipoic acid
amino acids
AMP-activated protein kinase (AMPK)
Angelica
anthocyanidins
anthocyanins
anthocyanosides
antler
Aralia
arginine alpha ketoglutarate
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arginine creatine
Arginine nitrate
Arginine silicate
arjun tree
arjuna
arjunic acid
Aronia melanocarpa
ashitaba
ashwagandha
asparagus
astaxanthin
Asteraceae
astragaloside
astragalus
atractylodes
atractylone
Auricularia
Autumn elaeagnus
Bassia scoparia
bee products
beet
bergamot
berry
bilberry
bioflavonoids
biota seed
birch
bishop\'s weed
black cumin
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black galingale
black garlic
black ginger
black pepper
black tea
blackboard tree
blueberry
Boerhavia diffusa
borneol
bromelain
Buckwheat
Buddha\'s hand
bupleurum falcatum
bur-reed
burdock
butcher's broom
Butea monosperma
Caesalpinia crista
caffeine
calycosin
capillary artemisia
capsaicin
capsaicinoids
capsicum
capsinoids
cardamom
carqueja
Carthamus
cat's claw
catecholamine
caterpillar mushroom
cayenne pepper
celery
Centella asiatica
Centella triterpenes
chen pi
cherry
chestnut
Chinese mountain ant
Chinese salvia root
Chinese silkvine
chocolate
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cinnamaldehyde
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cistanche
Citrus
citrus bioflavonoids
citrus sinensis (proprietary)
clove
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cola nut
Coleus forskohlii
commiphora
cordyceps
costus
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Curcuma
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currant
cyanidin
d-alpha tocopherol
danshen
date
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dioscorea
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Ilex
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inositol nicotinate
inula racemosa
iron
jiaogulan
knotweed
kola nut
kudzu
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l-carnitine
L-citrulline
Ligusticum
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lingzhi
long pepper
lovage
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mace
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mustard seed
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Niacinamide (vitamin B3)
nicotinamide riboside
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onion
orange
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oyster mushroom
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quercetin
reishi mushroom
resveratrol
rhizome
ribose
rockweed
Rosa roxburghii
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rosemary
Ruscogenins
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rutin
Rutosides
S-allylcysteine
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saponins
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Serrapeptase
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