Vitamin E, which includes both tocopherols and tocotrienols, has been investigated for its potential effects on circulation and vascular health. The interest in Vitamin E for circulation arises from its antioxidant properties, which can help prevent oxidative damage to blood vessels and lipids, a factor in the development of atherosclerosis and other vascular conditions. Some clinical studies suggest that Vitamin E supplementation may help reduce oxidative stress and improve endothelial function—both relevant to circulatory health. However, large-scale intervention trials in humans have produced mixed results, with many showing little to no benefit of Vitamin E supplementation in reducing cardiovascular events or improving circulation in otherwise healthy individuals or those with established vascular disease.

There is stronger evidence for tocotrienols (a subgroup of Vitamin E) to have additional benefits on lipid profiles and anti-inflammatory properties, but these findings are still emerging and largely preclinical or from small-scale human studies. Traditional use of Vitamin E specifically for circulation is not well-documented; its use is primarily based on mechanistic hypotheses and limited clinical evidence.

In summary, while Vitamin E is scientifically considered for vascular support due to its antioxidant effects, robust clinical evidence for its efficacy in improving poor circulation is limited. The rating reflects that there is scientific rationale and some supporting evidence, but not enough to strongly recommend its use for this purpose.