Evidence supporting the use of: Alpha-GPC
For the health condition: Circulation (to the brain)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Alpha-GCP (Alpha-glycerylphosphorylcholine, often referred to as Alpha-GPC) is a cholinergic compound that is primarily studied for its cognitive-enhancing properties. Its use to support or treat cerebral circulation (i.e., blood flow to the brain) is based on some scientific investigations, though most research focuses on its ability to increase levels of acetylcholine, a neurotransmitter involved in memory and learning. Some clinical studies, particularly from Europe, have explored the effects of Alpha-GPC in patients with cognitive decline, vascular dementia, or stroke. These studies suggest that Alpha-GPC may have a modest positive effect on cognitive function, potentially due to both its cholinergic activity and a possible influence on cerebral blood flow. However, the evidence directly linking Alpha-GPC to improved cerebral circulation is limited and not robust. Some small trials have noted improvements in neurological outcomes post-stroke, which may involve enhanced circulation, but larger, high-quality studies are lacking. The mechanism by which Alpha-GPC could influence circulation is not well established and may be secondary to its neuroprotective effects rather than a direct vasodilatory action. Overall, while there is some scientific investigation into Alpha-GPC’s role in brain health and possibly circulation, the quality and quantity of evidence specifically for cerebral circulation are limited, warranting a modest evidence rating.

More about Alpha-GPC
More about Circulation (to the brain)

Products containing Alpha-GPC

We currently have no products on Vitabase that contain this ingredient.