Evidence supporting the use of: Resveratrol analogue
For the body system: Circulatory System
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Resveratrol analogues are compounds structurally similar to resveratrol, a polyphenol found in grapes, berries, and peanuts. There is scientific interest in these analogues for their potential cardiovascular benefits. Preclinical studies (in vitro and animal models) have demonstrated that resveratrol and several analogues possess antioxidant, anti-inflammatory, and vasodilatory effects, which are mechanisms that could support circulatory health. Some analogues, such as pterostilbene, have shown greater bioavailability and similar or enhanced biological activity compared to resveratrol itself.
Human data are more limited. A few small clinical trials with resveratrol (not always specifically its analogues) have reported improvements in endothelial function, modest reductions in blood pressure, and favorable effects on cholesterol profiles. Evidence for analogues like pterostilbene is more preliminary but suggests potential for reducing blood pressure and improving lipid parameters. However, large-scale, long-term clinical trials are lacking, and the existing studies often suffer from limitations such as small sample size, short duration, and variability in dosing and formulation.
Overall, while there is promising preclinical evidence and some early clinical support for the use of resveratrol analogues in supporting the circulatory system, the current scientific evidence is moderate and not yet definitive. More robust human studies are needed to confirm efficacy and establish appropriate dosing guidelines.
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Other ingredients that support Circulatory System
ajoenealfalfa
algal oil
alpha-carotene
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
amino acids
anchovies
anthocyanins
apple
arjun tree
artichoke
ashwagandha
astaxanthin
astragalus
barley
basil
beet
berberine
bergamot
Beta-Glucan
bilberry
black cumin
black currant
black garlic
sesame
black tea
blackberry
blueberry
bonito peptide
bovine liver
broccoli
brussel sprouts
burdock
butcher's broom
caffeine
calamari oil
calcium
campesterol
canola oil
capsaicinoids
cassia bark
catechins
caterpillar mushroom
cauliflower
celery
cherry
chia seed
Chinese salvia root
chlorella
chokeberry
cinnamon
citrus bioflavonoids
citrus sinensis (proprietary)
coenzyme Q10 (CoQ10)
coleus forskohlii
collard
copper
cottonseed oil
cordyceps
turmeric
curcumin
cuspidatum root
d-alpha tocopherol
dandelion
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
dog rose
dong quai root
DPA (docosapentaenoic acid)
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ethanol
fennel
fenugreek
fiber blend (proprietary)
fisetin
fish oil
fish protein
flavonols
flaxseed
forskohlii root
fruit and vegetable blend (proprietary)
gamma linolenic acid (GLA)
gamma tocopherol
garlic bulb
ginger
ginkgo biloba
ginseng
gokhru
gooseberry
gotu kola
grape
greek mountain tea
onion
green tea
greens blend (proprietary)
guggul
hawthorn
hesperetin
hesperidin
hibiscus
horse chestnut
iron
knotweed
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kale
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kudzu
l-arginine
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l-citrulline
l-taurine
lignans
linoleic acid (LA)
luteolin
lycopene
mackerel
magnesium
mango
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marine lipid
matcha
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motherwort
mustard seed
naringin
nattokinase
nattozimes
nettle
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oat
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olive
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orange
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palmitoleic acid
pantethine
parsley
phenolic acids
phytosterols
pine bark
plant sterols
policosanol
pomegranate
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potassium
quercetin
quinoa
raspberry
red yeast rice
rehmannia glutinosa
reishi mushroom
resveratrol
rhizome
rose hips
rosemary
rutin
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sardines
scrophularia root
secoisolariciresinol diglucoside
selenium
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sitostanol
soybean
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spirulina
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strawberry
sulforaphane glucosinolate
thiamin (vitamin B1)
tocotrienols
tomato
trans-pterostilbene
trimethylglycine (TMG)
triphala
almond fruit
ubiquinol
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vegetable and fruit blend (proprietary)
vegetable blend (proprietary)
vinpocetine
vitamin B
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vitamin D
vitamin D3
vitamin E
vitamin K
seaweed
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watercress
watermelon
wheat grass
mulberry
β-nicotinamide mononucleotide (NMN)
sarsaparilla
red clover
suma
jiaogulan
tangerine
gastrodia
lobelia
capsicum
hedychium spicatum
inula racemosa
punarnava
commiphora
rubia cordifolia
bee pollen
peony
lingzhi
lingusticum wallichii
yarrow
prickly ash
morus
lemongrass
sodium salt
ferulic acid
chrysanthemum
eucommia
ganoderma
zanthoxylum
electrolytes blend (proprietary)
terpene lactones
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shepherd's purse
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noni
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algae
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kidney beans
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cayenne pepper
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Arjuna
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Animal Tissue
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Asiaticoside
Angelica
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Algal protein
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Ba Ji Tian
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bugleweed
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Caffeic Acid
Camellia sinensis
Centella triterpenes
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Chinese Mountain Ant
Cyanobacteria
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glucose
Mustard
Mistletoe
Periwinkle
Pistachio
Rose
Snakeroot (unspecified)
salt
Soy Protein
Sumac
Vervain
walnut
yohimbine
Other body systems supported by Resveratrol analogue
ArteriesBlood
Brain
Circulatory System
Heart
Mitochondria
Skin