Relationship: Circulatory System and selenium

Evidence supporting the use of: Selenium
For the body system: Circulatory System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Selenium is an essential trace mineral that plays a crucial role in various physiological processes, including antioxidant defense and thyroid hormone metabolism. Its relevance to the circulatory system largely centers on its incorporation into selenoproteins, such as glutathione peroxidase, which help protect cells—including those in the cardiovascular system—from oxidative damage. Oxidative stress is a known contributor to the development of atherosclerosis and other cardiovascular diseases. Several observational studies have noted an association between low selenium levels and an increased risk of cardiovascular events. In regions with selenium-deficient soils, such as parts of China, selenium supplementation has been linked to a decreased incidence of Keshan disease, a cardiomyopathy caused by selenium deficiency. However, large randomized controlled trials in populations with adequate selenium status, such as the U.S., have not consistently demonstrated a benefit of selenium supplementation for the prevention of heart disease or improvement in cardiovascular outcomes. Excessive selenium intake can also be harmful. Therefore, while the essentiality of selenium for cardiovascular health is well-established in deficiency states, the evidence for supplementation in individuals with sufficient selenium is limited. Overall, the use of selenium to support the circulatory system is scientifically justified in cases of deficiency, but routine supplementation for cardiovascular protection in the general population is not strongly supported by current evidence.

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Other body systems supported by selenium

Blood
Brain
Circulatory System
Female Reproductive System
Glandular System
Hair
Heart
Immune System
Liver
Male Reproductive System
Mitochondria
Nails
Prostate
Reproductive System
Reproductive System
Skin
Testes
Testosterone
Thyroid Gland

Products containing selenium

Health Concerns

Brands

Evidence supporting the use of: Selenium
For the body system: Circulatory System

Table of Contents

Synopsis

Other ingredients that support Circulatory System

Other body systems supported by selenium

Products containing selenium

Health Concerns

Brands

Evidence supporting the use of: SeleniumFor the body system: Circulatory System

Table of Contents

Synopsis

Other ingredients that support Circulatory System

Other body systems supported by selenium

Products containing selenium

Evidence supporting the use of: Selenium
For the body system: Circulatory System