Relationship: Circulatory System and vitamin D3

Evidence supporting the use of: Vitamin D3
For the body system: Circulatory System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin D3 (cholecalciferol) is primarily recognized for its role in calcium and bone metabolism, but emerging research supports its relevance to the circulatory (cardiovascular) system. Scientific studies have shown that vitamin D receptors are present in various cardiovascular tissues, including the endothelium, vascular smooth muscle, and cardiomyocytes. Epidemiological data indicate a correlation between low serum vitamin D levels and an increased risk of hypertension, coronary artery disease, heart failure, and stroke. Some interventional studies suggest that vitamin D supplementation may modestly lower blood pressure in individuals with deficiency and could have beneficial effects on vascular function and inflammation markers. However, large randomized controlled trials have produced mixed results regarding its impact on major cardiovascular events, and current evidence does not support high-dose supplementation specifically for cardiovascular prevention in the general population. Clinical guidelines recommend vitamin D supplementation primarily for bone health, but acknowledge that maintaining adequate vitamin D status may have indirect cardiovascular benefits, particularly in those with deficiency. In summary, there is moderate scientific evidence linking vitamin D3 to circulatory system health, but its use as a primary intervention for cardiovascular disease is not strongly established.

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beet
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bonito peptide
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dandelion
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diallyl disulfide (DADS)
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dong quai root
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eleuthero
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ethanol
fennel
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Other body systems supported by vitamin D3

Blood
Brain
Circulatory System
Glandular System
Heart
Immune System
Intestinal System
Kidneys
Lungs
Mitochondria
Muscles
Parathyroid Glands
Respiratory System
Skeletal System (Bones)
Skin
Small Intestines
Teeth

Products containing vitamin D3

Health Concerns

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Evidence supporting the use of: Vitamin D3
For the body system: Circulatory System

Table of Contents

Synopsis

Other ingredients that support Circulatory System

Other body systems supported by vitamin D3

Products containing vitamin D3

Health Concerns

Brands

Evidence supporting the use of: Vitamin D3For the body system: Circulatory System

Table of Contents

Synopsis

Other ingredients that support Circulatory System

Other body systems supported by vitamin D3

Products containing vitamin D3

Evidence supporting the use of: Vitamin D3
For the body system: Circulatory System