Evidence supporting the use of: Artichoke
For the health condition: Cirrhosis of the Liver

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Artichoke (Cynara scolymus) has a long history of use in traditional medicine, particularly in Mediterranean and European herbal practices, for supporting liver health and treating disorders such as cirrhosis. Traditional healers valued artichoke for its purported ability to stimulate bile production, support digestion, and protect the liver from toxins and disease. The use of artichoke for liver conditions like cirrhosis is rooted in these folk practices, dating back to at least the 16th century. Modern research has identified some bioactive compounds in artichoke, such as cynarin and silymarin, which exhibit antioxidant and hepatoprotective effects in vitro and in animal studies. However, clinical studies specifically addressing artichoke’s efficacy in treating or reversing cirrhosis in humans are sparse and generally of low quality or small sample size. Most available human research focuses on general liver support, mild dyspepsia, or hypercholesterolemia, rather than established cirrhosis. Therefore, while the use of artichoke for cirrhosis has a strong traditional foundation, robust scientific evidence to support its effectiveness for this specific condition is lacking. Artichoke may be considered as a supportive therapy for general liver health, but should not replace proven medical treatments for cirrhosis. Anyone considering its use for liver disease should consult a healthcare provider.

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