Evidence supporting the use of: Fungus
For the health condition: Cirrhosis of the Liver

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Fungi, particularly certain medicinal mushrooms such as Ganoderma lucidum (Reishi), Cordyceps sinensis, and Poria cocos, have a long-standing history in traditional Chinese medicine (TCM) and other Asian medical systems for supporting liver health, including the treatment of liver diseases like cirrhosis. In TCM, these mushrooms are often prescribed as hepatoprotective agents, believed to enhance liver function, reduce inflammation, and improve energy levels in patients with chronic liver ailments. The traditional rationale is based on hundreds of years of empirical use, as documented in classical medical texts. However, while there is a growing body of preclinical research indicating that certain fungal extracts may have antioxidant, immunomodulatory, and antifibrotic properties, high-quality clinical trials in humans with cirrhosis are limited and results are often preliminary or inconclusive. Thus, the main justification for their use in cirrhosis remains rooted in tradition rather than robust scientific validation. Patients should always consult healthcare providers before using such supplements, as their efficacy and safety for serious conditions like cirrhosis are not definitively established by modern evidence.

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