Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Goji berry (Lycium barbarum) has a long history of use in traditional Chinese medicine (TCM), where it is believed to support liver health and overall vitality. In TCM, goji berries are included in formulas to "nourish the liver and kidney," and their use for chronic liver conditions, including cirrhosis, is documented in several classical texts. The rationale stems from the belief that goji berries can "tonify" the liver, improve blood quality, and support the body's yin, which is often considered depleted in chronic illnesses.

However, modern scientific research supporting the efficacy of goji berry specifically for cirrhosis of the liver is limited. Some in vitro and animal studies suggest that goji berry polysaccharides may have hepatoprotective effects, such as reducing oxidative stress, modulating immune responses, and potentially inhibiting fibrotic processes in the liver. For example, a few studies in rodents have shown that extracts from goji berries can mitigate chemically induced liver injury and fibrosis. Nevertheless, clinical evidence in humans is sparse, and there are no large, well-controlled trials demonstrating a clear benefit for patients with cirrhosis.

In summary, goji berry is used for liver support based on traditional practices, with some preliminary scientific data suggesting potential hepatoprotective properties. For cirrhosis specifically, the evidence remains weak and largely preclinical, warranting a rating of 2 on the evidence scale.

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