Evidence supporting the use of: Phospholipids (unspecified)
For the health condition: Cirrhosis of the Liver
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Phospholipids, particularly in the form of "essential phospholipids" (EPL), have been studied for their potential role in the management of liver diseases, including cirrhosis. The rationale for their use is based on the idea that phospholipids are key components of cellular membranes, and supplementation may help restore membrane integrity in damaged liver cells. Several clinical trials, primarily conducted in Eastern Europe and Asia, have investigated the use of EPLs (often derived from soybeans) in patients with chronic liver diseases, including cirrhosis. Some studies have reported improvements in biochemical markers of liver function (such as ALT, AST, and bilirubin levels), as well as histological findings and symptoms. However, many of these studies have significant methodological limitations, including small sample sizes, lack of blinding, and inconsistent outcome measures.
Systematic reviews and meta-analyses have concluded that while there is some evidence suggesting a potential benefit of phospholipids in liver disease, the overall quality of evidence is low and findings are inconsistent. Major liver disease guidelines, including those from the American Association for the Study of Liver Diseases (AASLD) and the European Association for the Study of the Liver (EASL), do not recommend phospholipids as standard therapy for cirrhosis due to insufficient high-quality evidence. In summary, while there is some scientific investigation and modest tradition of use, robust clinical validation is lacking, and phospholipids are not universally endorsed for the treatment of cirrhosis.
More about Phospholipids (unspecified)
More about Cirrhosis of the Liver
Other ingredients used for Cirrhosis of the Liver
alpha-ketoglutarate (AKG)artichoke
astaxanthin
branched-chain amino acids
bupleurum falcatum
burdock
caterpillar mushroom
turmeric
curcumin
dandelion
flavonols
garlic bulb
ginger
green tea
Indian tinospora
l-glutathione
licorice root
liquid liver fractions
milk thistle
n-acetyl-cysteine (NAC)
oleanolic acid
phospholipids
quercetin
reishi mushroom
resveratrol
selenium
silymarin
spirulina
vitamin B
vitamin E
seaweed
zinc
sarsaparilla
punarnava
picrorhiza kurroa
buckthorn
morus
dodder
ganoderma
goji berry
Antrodia camphorata
Borotutu
Bael
bile acid
Boerhavia diffusa
Coriolus mushroom
Curcuminoid
Cynarin
Cowherb
Eupolyphaga sinensis
Fucoidan
Flavonolignan
Other health conditions supported by Phospholipids (unspecified)
Cancer Treatment (reducing side effects)Cholesterol (high)
Cirrhosis of the Liver
Dermatitis
Fatigue
Fatty Liver Disease
Gastritis
Hepatitis
Inflammation
Liver Detoxification
Memory and Brain Function
Nerve Damage
Skin Care (general)
Triglycerides (high)
Ulcers
Wounds and Sores