Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Herbal blends have been traditionally used to support or treat cold sores, primarily drawing from historical and folk medicine practices. Various herbs such as lemon balm (Melissa officinalis), licorice root (Glycyrrhiza glabra), echinacea, and others have featured in topical or oral remedies aimed at reducing the frequency, severity, or duration of herpes simplex virus (HSV) outbreaks that cause cold sores. For example, lemon balm extract has a long tradition of topical application for cold sores in European herbalism, based on its reputed antiviral and soothing properties. Licorice root also appears in traditional Chinese medicine and Western herbalism for similar uses, attributed to its glycyrrhizin content.

However, clinical evidence supporting these uses is limited and often of low quality. Some small studies suggest that lemon balm may reduce healing time and symptoms when applied at the first sign of an outbreak, but these findings are preliminary. There is little robust data supporting the efficacy of most herbal blends as a whole, particularly proprietary mixtures, as these often contain varying ingredients and concentrations. Overall, while the use of herbal blends for cold sores is rooted in tradition and some individual components show promise, definitive scientific validation is lacking. Thus, the evidence rating is 2 out of 5, reflecting traditional use with limited preliminary scientific support.

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