Evidence supporting the use of: Apigenin
For the health condition: Colds (antiviral)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Apigenin is a naturally occurring flavonoid found in many plants such as parsley, chamomile, and celery. Its use for colds is primarily based on its in vitro antiviral and anti-inflammatory properties, rather than a long-standing tradition of use specifically for respiratory viral infections. Several laboratory studies have demonstrated that apigenin can inhibit the replication of certain viruses, including influenza A and some common cold viruses, by interfering with viral entry or replication and modulating host immune responses. Apigenin has also been shown to reduce the production of pro-inflammatory cytokines, which may help alleviate some symptoms associated with colds.
However, despite these promising mechanisms, there is a lack of robust human clinical trials directly assessing apigenin’s effectiveness for treating or preventing common colds. Most available evidence is preclinical and does not yet translate to clear clinical benefit in humans. Therefore, while the use of apigenin for colds is supported by preliminary scientific evidence, especially from laboratory studies, its efficacy in real-world use remains unproven and requires further investigation. As such, the evidence rating is 2/5, reflecting potential but unconfirmed benefits.
Other ingredients used for Colds (antiviral)
AcacetinAgastache
AHCC
Allicin
Alliin
Allium tuberosum
Allspice
Allyl isothiocyanate
Allyl sulfide
Aloe vera
alpha-terpineol
alpinia galangal
amentoflavone
anamu
Andrographis
andrographolide
anthocyanins
apigenin
arabinogalactan
Asam gelugor
ash
Asteraceae
atractylone
Aureobasidium pullulans
Autumn elaeagnus
baicalin
Baikal Skullcap
balsam
Baphicacanthus cusia
Basidiomycota
basil
Bassia scoparia
bee hive
bee products
bee propolis
berry
beta-pinene
Bidens pilosa
bilberry
bishop\'s weed
bitter grass
black cumin
black currant
black galingale
black garlic
black nightshade
black seed
blueberry
Bombax
borneol
Broussonetia
buckthorn
caffeic Acid
Camellia sinensis
capillary artemisia
carrageenan
carvacrol
cat's claw
catechins
Celosia
Chinese mountain ant
Chinese raisintree
Chondrus
chrysanthemum
cinnamaldehyde
cinnamon
Cistus
citron
Citrus
citrus bioflavonoids
Clerodendrum trichotomum
clove
coconut
commiphora
common madia
coriolus mushroom
costus
cowherb
curry leaf
David\'s milkberry
deoxyandrographolides
Echinacea
echinacea purpurea
Elder
elderberry
epigallocatechin gallate (EGCG)
essential oil blend
European Elder
flavones
flavonoids
flavonones
forsythia
fruit
fulvic acid
fungus
Galangal
Gallesia
gallotannin
gamma-terpinene
ganoderma
garlic
garlic bulb
ginger
glyceryl monolaurate
Glycyrrhetinic acid
Glycyrrhizin
goji berry
goldthread
green tea
Hedyotis
Himalaya berry
honey
honey loquat syrup
honeysuckle
Houttuynia
hyssop
Indian frankincense
Indian kinotree
indigo leaves
Isatis
knotweed
labrador tea
Lactoferrin
Lactoperoxidase
Laggera pterodonta
lauric acid
lemon
lemongrass
lichen
licorice root
Ligusticum
ligustilides
Ligustrum
Litsea
liverwort
Lomatium
luffa
luteolin
mangostin
Mastic gum
Melia
Mineral ascorbate
Monolaurin
Monoterpenes
Morinda
Morus
Mugwort
Mushroom
Naphthoquinones
Neem tree
Neoandrographolides
nut grass
Nymphaea nouchali
oregano
oriental arborvitae
Osha
Osmanthus
Oxystelma
papaya
Paris polyphylla
Patrinia
pau d'arco
perilla
Petiveria
Phaeophyceae
Phellodendron
phellodendron amurense
phenolic compounds
Phenylpropanoids
Phyllanthus
pineapple
Piper nigrum
Polygonum
pomegranate
Propolis
quercetin
ravinsara
resveratrol
rhizome
rosemary
Salvia
Sambucus nigra
Sandalwood
saponins
schizonepeta
Sesquiterpenes
shiitake mushroom
Shikimic Acid
Shogaol
Smartweed
Solanaceae
Solanum indicum
Sophora
soursop
spirulina
Tagetes
Tamaricaceae
Tayuya
Tea
Terpenoids
Theaflavin
Thiosulfinate
thyme
Thymus
Trametes
Triterpenes
turmeric
Verbascoside
Viola
Violet
Visnea Mocanera
vitamin C
vitamin D
Wasabi
Waterhyssop
White Tea
xanthium (cockleburs)
Xanthorrhizol
zanthoxylum
Zinc
Zingiberene
Other health conditions supported by apigenin
Aging (prevention)Alzheimer's Disease
Anxiety
Anxiety Disorders
Arthritis
Asthma
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Colds (antiviral)
Colitis
Depression
Diabetes
Diabetic Retinopathy
Fatty Liver Disease
Fibrosis
Free Radical Damage
Gastritis
Hypertension
Inflammation
Inflammatory Bowel Disorders
Insomnia
Liver Detoxification
Memory and Brain Function
Metabolic Syndrome
Nerve Damage
Osteoporosis
Parkinson's Disease
Psoriasis
Rheumatoid Arthritis
Stress
Ulcers
