Evidence supporting the use of: Apigenin
For the health condition: Colds (antiviral)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Apigenin is a naturally occurring flavonoid found in many plants such as parsley, chamomile, and celery. Its use for colds is primarily based on its in vitro antiviral and anti-inflammatory properties, rather than a long-standing tradition of use specifically for respiratory viral infections. Several laboratory studies have demonstrated that apigenin can inhibit the replication of certain viruses, including influenza A and some common cold viruses, by interfering with viral entry or replication and modulating host immune responses. Apigenin has also been shown to reduce the production of pro-inflammatory cytokines, which may help alleviate some symptoms associated with colds.

However, despite these promising mechanisms, there is a lack of robust human clinical trials directly assessing apigenin’s effectiveness for treating or preventing common colds. Most available evidence is preclinical and does not yet translate to clear clinical benefit in humans. Therefore, while the use of apigenin for colds is supported by preliminary scientific evidence, especially from laboratory studies, its efficacy in real-world use remains unproven and requires further investigation. As such, the evidence rating is 2/5, reflecting potential but unconfirmed benefits.

More about Apigenin
More about Colds (antiviral)

Other ingredients used for Colds (antiviral)

Allspice
Aloe vera
anthocyanins
arabinogalactan
waterhyssop
basil
berry flavor
beta-pinene
bilberry
bisabolol
black cumin
black currant
black garlic
blueberry
Indian frankincense
cat's claw
catechins
cinnamon
citrus bioflavonoids
citrus oil
clove
turmeric
echinacea purpurea
elderberry
epigallocatechin gallate (EGCG)
forsythia
garlic bulb
ginger
green tea
honeysuckle
knotweed
lactoferrin
lactoperoxidase
lauric acid
lemon
licorice root
luteolin
mastic gum
monolaurin
oregano
perilla
phellodendron amurense
phenolic compounds
pineapple
pomegranate
quercetin
resveratrol
rhizome
rosemary
schizonepeta
shiitake mushroom
spirulina
thyme
vitamin C
vitamin D
Wasabi
zinc
xanthium (cockleburs)
hyssop
papaya
mugwort
neem tree
nut grass
alpinia galangal
commiphora
buckthorn
pau d'arco
morus
lemongrass
chrysanthemum
ganoderma
morinda
oriental arborvitae
zanthoxylum
fulvic acid
goji berry
indigo leaves
soursop
Ash
Agastache
Autumn elaeagnus
Alpha-terpineol
Apigenin
Allicin
Anamu
AHCC
Andrographolide
Amentoflavone
Asam gelugor
Acacetin
Aureobasidium pullulans
Andrographis
Asteracea
Allyl Sulfide
Allyl isothiocyanate
Alliin
Allium tuberosum
Atractylone
Bee Propolis
Black Seed
Baikal Skullcap
Baphicacanthus cusia
Bidens pilosa
Broussonetia
Balsam
Bishop's Weed
Black galingale
Bitter Grass
Bee hive
Basidiomycota
berry
Bee products
Black Nightshade
Bombax
Baicalin
Bassia scoparia
Borneol
Caffeic Acid
Camellia sinensis
Coconut
Curry leaf
Chinese Mountain Ant
Clerodendrum trichotomum
Coriolus mushroom
Carrageenan
Carvacrol
Capillary Artemisia
Citron
Citrus
Chinese Raisintree
Cowherb
Cistus
Common madia
Cinnamaldehyde
Costus
Celosia
Chondrus
Deoxyandrographolides
David's Milkberry
European Elder
Echinacea
Elder
Essential Oil Blend
Fruit
Flavonoids
Fungus
Flavonones
Flavones
Goldthread
Glyceryl monolaurate
gamma-terpinene
Garlic
Gallesia
Gallotannin
Glycyrrhetinic Acid
Galangal
Glycyrrhizin
Honey
Hedyotis
Houttuynia
Honey loquat syrup
Himalaya Berry
Isatis
Indian Kinotree
Litsea
Lomatium
Lichen
Laggera pterodonta
Ligustilides
Luffa
Ligustrum
Labrador Tea
Liverwort
Ligusticum
Mineral ascorbate
Melia
Monoterpenes
Mangostin
Mushroom
Neoandrographolides
Naphthoquinones
Nymphaea nouchali
Osha
Osmanthus
Oxystelma
Propolis
Phellodendron
Phyllanthus
Phenylpropanoids
Phaeophyceae
Paris polyphylla
Piper nigrum
Patrinia
Polygonum
Petiveria
Ravinsara
Reed Herb
Sophora
Smartweed
Solanaceae
Sesquiterpenes
Salvia
Solanum indicum
Sambucus nigra
Shogaol
Sandalwood
saponins
Shikimic Acid
Terpenoids
Tea
Thymus
Tamaricaceae
Triterpenes
Tayuya
Theaflavin
Trametes
Tagetes
Thiosulfinate
Visnea Mocanera
Violet
Verbascoside
Viola
White Tea
Xanthorrhizol
Zingiberene

Products containing Apigenin

We currently have no products on Vitabase that contain this ingredient.