Evidence supporting the use of: Cineole
For the health condition: Colds (decongestant)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Cineole (also known as eucalyptol) is a natural organic compound found in eucalyptus oil and other plant essential oils. Its use as a decongestant for supporting or treating colds is supported by scientific evidence. Several randomized controlled trials and clinical studies have investigated cineole’s effects on upper respiratory tract infections, including the common cold. Cineole exhibits mucolytic (mucus-thinning), anti-inflammatory, and mild bronchodilatory properties, which contribute to its decongestant effects.

One notable double-blind, placebo-controlled study published in Respiratory Medicine (2004) found that patients with acute bronchitis who were treated with cineole showed significant improvement in symptoms such as cough frequency and nasal congestion compared to placebo. Additionally, in vitro studies have demonstrated that cineole can inhibit the production of inflammatory mediators, which may help reduce swelling of the mucous membranes and ease breathing.

Cineole is commonly administered via inhalation (aromatherapy) or oral capsules in Europe for respiratory complaints, and is an active ingredient in several over-the-counter cold remedies. Its efficacy and safety have been reviewed in systematic analyses, which generally conclude that cineole is beneficial for relieving symptoms of colds, especially nasal congestion, when used appropriately. However, while evidence is robust for symptom relief, cineole is not curative for viral infections themselves.

More about Cineole
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