Evidence supporting the use of: Phenolic acids
For the health condition: Colds (general)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Phenolic acids, a group of plant-derived compounds (including caffeic acid, ferulic acid, and gallic acid), have traditionally been used in herbal remedies for colds and related respiratory ailments. Their inclusion in traditional medicine is largely due to their presence in commonly used medicinal plants such as elderberry, echinacea, and various berries and herbs. Historically, these plants were brewed into teas or used in tinctures to alleviate cold symptoms, and phenolic acids are considered among their active components due to their antioxidant and mild anti-inflammatory properties.

However, direct scientific evidence supporting the use of isolated phenolic acids specifically for treating or preventing the common cold is limited. Most research focuses on their general immunomodulatory and antiviral potentials, as well as their ability to combat oxidative stress, which may indirectly support immune function. Some in vitro and animal studies suggest that phenolic acids can modulate immune responses and inhibit replication of certain viruses, but robust clinical trials in humans specific to cold treatment are lacking. Thus, while their use is rooted in traditional herbal medicine, and there is some plausible biological rationale, the evidence supporting their effectiveness for colds is modest and primarily based on traditional practice rather than strong clinical validation.

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Other ingredients used for Colds (general)

aloe vera
anthocyanins
blueberry
black currant
elderberry
garlic bulb
ginger
grape
green tea
licorice root
pomegranate
quercetin
spirulina
zinc
turmeric
vitamin D
vitamin C
abies spectabilis
Abrus
Agastache
Alcohol
Allicin
Alliin
Alpha-terpineol
Amor seco
Andrographis
Andrographolide
Angelica
Apple Cider Vinegar
Aralia
acacia
Aconite
Allium tuberosum
allspice
allyl isothiocyanate
Allyl Sulfide
alpinia galangal
American Liverleaf
Anamu
apple
arabinogalactan
Asarum heterotropoides
Asteracea
atractylodes
Atractylone
Avens
Baccharoides anthelmintica
bamboo
Banyan
Baphicacanthus cusia
barberry
Barleria
basil
Bassia scoparia
Bayleaf
Bee hive
Bee products
Belamcanda
berry
berry flavor
beta-pinene
Bidens pilosa
Bioflavonoids
birch
Bishop's Weed
Bitter Grass
Bitter principals
black cumin
black garlic
Black Nightshade
black pepper
Black Seed
black tea
blackberry
blackboard tree
Blackthorn
Blepharis
Boerhavia diffusa
Bombax
Borassus Palm
Borneol
Bougainvillea
Aerva lanata
Ajuga
algae
Amomum
Arani
Ardisia
Asam gelugor
Ash
aster root
astragalus
Bael
Baikal Skullcap
Balsam
bee pollen
Bee Propolis
benegut perilla (proprietary)
Bermuda Grass
Black galingale
black salt
boneset
Borassus aethiopum
boxthorne
buckthorn
bupleurum falcatum
burdock
bасора
capsaicinoids
capsicum
cardamom
carrot
cassia bark
caterpillar mushroom
cayenne pepper
chamomile
chrysanthemum
Cinnamomum
cinnamon
citrus oil
citrus sinensis (proprietary)
clove
coconut milk
colostrum
commiphora
Curcuminoid
dodder
dog rose
dulse leaf
echinacea purpurea
Elder
eucalyptus
European Elder
ferula assafoetida
flowering quince
forsythia
fulvic acid
Garlic
ginseng
gooseberry
greek mountain tea
green chiretta
greens blend (proprietary)
honeysuckle
horehound
horseradish
hyacinth bean
hyssop
Indian bael
Indian tinospora
indigo leaves
jujube
l-cysteine
lactiplantibacillus plantarum
lactobacillus fermentum
lactobacillus reuteri
lemon
lemongrass
lingusticum wallichii
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lovage
lychee
marshmallow
mastic gum
menthol oil
milk
morinda
moringa
mugwort
Mustard
mustard seed
neem tree
nettle
nut grass
onion
orange
oregano
oregon grape
papaya
paw paw
peach
pear
peony
perilla
phellodendron amurense
phenolic acids
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pistacia integerrima gall
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plum fruit
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quail egg
radish
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reishi mushroom
rhizome
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sage
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sarsaparilla
schizonepeta
scrophularia root
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siler root
spearmint leaf
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spruce
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squawvine
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typhonium
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vitamin B
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xanthium (cockleburs)
yeast
yerba santa
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