Evidence supporting the use of: Scrophularia root
For the health condition: Colds (general)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Scrophularia root, also known as Chinese Figwort or Xuan Shen (玄参), has a long history of use in Traditional Chinese Medicine (TCM) for treating various ailments, including symptoms associated with general colds. In TCM, Scrophularia is considered a "cooling" herb that is believed to clear heat, reduce toxicity, and nourish yin. It is often included in herbal formulas intended to address sore throat, fever, and swollen glands—all common symptoms of upper respiratory tract infections and colds. However, this use is primarily grounded in traditional practice rather than robust scientific validation.

Modern pharmacological research on Scrophularia root is limited. Some in vitro and animal studies have suggested it contains iridoid glycosides and other compounds with anti-inflammatory and immunomodulatory properties, which could theoretically help with symptoms of the common cold. Nevertheless, there are no well-designed clinical trials or systematic reviews that specifically support its efficacy for treating or preventing general colds in humans. Most available evidence comes from traditional usage reports and small laboratory studies, which do not meet the standards of modern clinical research.

In summary, while Scrophularia root is traditionally used to help with colds and related symptoms, the scientific evidence supporting this use is limited and indirect. Anyone considering its use should consult a healthcare professional, particularly since traditional remedies may interact with other medications or have contraindications.

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Products containing scrophularia root

Metagenics Serenagen®
Metagenics Serenagen