Evidence supporting the use of: Vitamin D (cholecalciferol)
For the health condition: Colds (prevention)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin D (cholecalciferol) has been studied for its potential role in preventing acute respiratory tract infections, including the common cold. The interest in vitamin D for cold prevention stems from its immunomodulatory effects: vitamin D receptors are present on various immune cells, and vitamin D is involved in promoting innate immune responses while modulating inflammation. Epidemiological studies have shown that people with lower vitamin D levels may have an increased susceptibility to respiratory infections.

Several randomized controlled trials (RCTs) and meta-analyses have evaluated whether vitamin D supplementation reduces the risk of colds and other respiratory infections. A notable individual patient data meta-analysis published in the BMJ (2017) pooled data from 25 RCTs and found that vitamin D supplementation was associated with a modest reduction in the risk of acute respiratory tract infections, particularly among individuals with baseline vitamin D deficiency. However, the benefit appeared less pronounced or absent in those with sufficient baseline levels.

While results across studies are somewhat mixed, and the effect size is generally modest, there is scientific evidence—especially for people who are deficient in vitamin D—that supplementation can help reduce the incidence of respiratory infections, including colds. Current guidelines do not recommend universal vitamin D supplementation solely for cold prevention in the general population, but maintaining adequate vitamin D status is considered beneficial for overall immune health.

More about Vitamin D (cholecalciferol)
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Other ingredients used for Colds (prevention)

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aloe vera
green chiretta
anthocyanins
arabinogalactan
astragalus
waterhyssop
bamboo
basil
berry flavor
beta-pinene
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black cumin
black currant
black pepper
black tea
blackberry
bасора
camu camu
capsaicinoids
caterpillar mushroom
chamomile
chlorella
cinnamon
citrus bioflavonoids
citrus oil
citrus sinensis (proprietary)
clove
coconut milk
colostrum
turmeric
echinacea purpurea
elderberry
forsythia
garlic bulb
ginger
grape
greek mountain tea
onion
green tea
greens blend (proprietary)
Indian tinospora
honeysuckle
lactobacillus brevis
lemon
licorice root
lovage
marshmallow
moringa
mustard seed
nettle
spruce
orange
oregano
oregon grape
pear
phenolic acids
pineapple
plantain
pollen
pomegranate
pumpkin
quercetin
reishi mushroom
rhizome
rose hips
rosemary
sage
schizonepeta
scrophularia root
sphaeranthus indicus
thyme
vegetable blend (proprietary)
vitamin C
vitamin D
seaweed
yeast
zinc
sarsaparilla
squawvine
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xanthium (cockleburs)
papaya
mugwort
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alpinia galangal
ferula assafoetida
pistacia integerrima gall
blackboard tree
peony
buckthorn
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yerba santa
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flowering quince
sweet flag
hyacinth bean
eucalyptus
menthol oil
aster root
goji berry
paw paw
algae
indigo leaves
cayenne pepper
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Products containing Vitamin D (cholecalciferol)

We currently have no products on Vitabase that contain this ingredient.