Evidence supporting the use of: Capsaicinoids
For the health condition: Colds (with fever)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Capsaicinoids, the active compounds in chili peppers responsible for their heat, have a long history of use in traditional medicine, particularly in Asia and Central/South America. Traditional practices have used hot peppers or capsaicin-containing preparations to help with symptoms of colds and fevers. The rationale is based on the ability of spicy foods to induce sweating (diaphoresis), which is believed in some cultures to help "break" a fever. Additionally, capsaicin is known to stimulate mucus secretion, which may help clear nasal passages, providing some symptomatic relief for congestion associated with colds.

However, scientific evidence supporting the use of capsaicinoids specifically for treating colds with fever is limited. While capsaicin nasal sprays have demonstrated some benefit in reducing symptoms of non-allergic rhinitis and in relieving nasal congestion, there is little direct research on their effectiveness during viral colds accompanied by fever. Most clinical data focuses on pain relief, neuropathic conditions, or topical use for musculoskeletal pain. The traditional use is supported by anecdotal reports and cultural practices, but current clinical guidelines do not recommend capsaicinoids as a treatment for viral upper respiratory infections with fever.

In summary, while the use of capsaicinoids for colds with fever is rooted in tradition and may offer mild symptomatic relief (such as decongestion and sweating), scientific validation is weak and evidence quality is low (rating: 2/5).

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Products containing capsaicinoids

Douglas Laboratories Metabolic Lean