Evidence supporting the use of: Five-Leaf Cassia
For the health condition: Colds (with fever)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Five-Leaf Cassia (Cassia alata, also known as Senna alata) has a long history of use in traditional medicine systems, particularly in Southeast Asia and parts of Africa. Traditionally, its leaves have been prepared as decoctions or infusions to help manage symptoms of colds and fevers. Ethnobotanical records indicate that healers and local practitioners have recommended Five-Leaf Cassia for its perceived "cooling" properties, which are believed to help reduce fever and alleviate discomfort associated with common colds. The plant contains various bioactive compounds, such as anthraquinones and flavonoids, that may have mild antimicrobial or anti-inflammatory effects, though these are better documented for skin conditions than for respiratory illnesses.

However, scientific research directly evaluating the efficacy of Five-Leaf Cassia for treating colds or fevers is limited. Most of the available studies focus on its use as a laxative or as a topical treatment for fungal and bacterial skin infections. There is a lack of high-quality clinical trials or pharmacological studies supporting its benefit for colds with fever. Therefore, while its use is well rooted in traditional medicine, scientific validation for this specific application is lacking, and the evidence strength is rated as 2 out of 5, reflecting anecdotal and traditional support without rigorous scientific confirmation.

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