Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Pistacia integerrima, commonly known as Kakad Singhi, has a long history of use in traditional Ayurvedic and Unani medicine systems, particularly in South Asia, for treating respiratory ailments including coughs, colds (often with fever), and asthma. The primary part used is the gall or excrescence formed on the plant, believed to possess anti-inflammatory, antimicrobial, and expectorant properties. Traditional formulations often employ the powdered galls either alone or in combination with other herbs to alleviate symptoms of cold, fever, and throat irritation.

Scientific studies on Pistacia integerrima are limited, but some in vitro and animal studies suggest the presence of bioactive compounds like flavonoids and tannins that exhibit antimicrobial and anti-inflammatory effects. These pharmacological actions provide a plausible mechanistic basis for the traditional use of the galls in respiratory infections. However, robust human clinical trials are lacking, and most evidence remains preclinical or anecdotal. Thus, the use of Pistacia integerrima galls for colds with fever is primarily justified by tradition, with some preliminary scientific rationale but without strong clinical evidence.

In summary, while traditional medicine supports the use of Pistacia integerrima gall for respiratory conditions including colds with fever, scientific validation is weak and primarily limited to laboratory studies. Its use should be approached with caution, and further research is needed to establish efficacy and safety in humans.

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