Evidence supporting the use of: Sesquiterpenes
For the health condition: Colds (with fever)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Sesquiterpenes are a class of naturally occurring compounds found in many essential oils, such as those from ginger, chamomile, and myrrh. Their use for supporting or treating colds, especially those accompanied by fever, is primarily rooted in traditional herbal and folk medicine practices. Historically, plants rich in sesquiterpenes have been used for their purported anti-inflammatory, antipyretic (fever-reducing), and antimicrobial properties. For example, ginger (Zingiber officinale) and chamomile (Matricaria chamomilla), both containing significant sesquiterpene fractions, have long been ingredients in teas and remedies for respiratory infections and feverish colds.

From a scientific perspective, there is limited but emerging evidence that certain sesquiterpenes possess anti-inflammatory and mild antimicrobial activity in vitro or in animal studies. However, robust clinical data in humans, specifically related to the treatment or support of colds with fever, remain scarce. Most commonly cited studies address the general anti-inflammatory or immune-modulating effects of sesquiterpenes, rather than direct efficacy against cold viruses or fever reduction in humans. Thus, while the traditional basis for their use is strong, the scientific validation is incomplete, and the overall evidence would be rated as modest.

More about Sesquiterpenes
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Products containing Sesquiterpenes

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