Evidence supporting the use of: American Wormseed
For the health condition: Colic (children)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

American Wormseed (Chenopodium ambrosioides) has a long history of traditional use in various cultures, primarily for its anthelmintic (anti-parasitic) properties. In traditional medicine, particularly among Native American groups and in early American herbalism, wormseed was sometimes employed to treat gastrointestinal complaints in children, including colic, which was often attributed to intestinal worms or digestive disturbances. However, this use was based on empirical tradition rather than scientific evaluation. There is little to no robust scientific evidence supporting the efficacy or safety of American Wormseed for treating colic in children. In fact, due to the potential toxicity of its active compounds (such as ascaridole), its use in children has fallen out of favor and is generally discouraged in modern herbal medicine. Historical texts and ethnobotanical records confirm its traditional use, but modern clinical studies are lacking, and safety concerns further limit its recommendation for pediatric colic. Therefore, the evidence supporting its use for this indication is minimal and rooted primarily in tradition rather than validated research.

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