Evidence supporting the use of: Bacillus
For the health condition: Colitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bacillus species, particularly Bacillus clausii and Bacillus coagulans, have garnered scientific interest as probiotics for gastrointestinal conditions, including colitis. There is preliminary evidence from animal models and limited human studies suggesting that certain Bacillus strains may exert anti-inflammatory effects, help modulate the gut microbiota, and enhance intestinal barrier function. For example, some studies using Bacillus coagulans in animal models of colitis have shown reduced inflammation and improved histological outcomes. There are also small clinical trials and case reports indicating that supplementation with Bacillus clausii or Bacillus coagulans may alleviate symptoms in patients with inflammatory bowel disease, including ulcerative colitis, primarily by reducing diarrhea and improving stool consistency.

However, the quality and quantity of clinical evidence are limited. Most human studies have small sample sizes, short durations, and often combine Bacillus with other probiotic strains, making it difficult to attribute benefits specifically to Bacillus. Systematic reviews and meta-analyses generally conclude that while Bacillus-based probiotics show promise, more rigorous, large-scale, placebo-controlled trials are needed to confirm efficacy and establish guidelines for their use in colitis. Thus, there is some scientific validation, but the overall strength of evidence remains modest (rated 2/5).

More about Bacillus
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Acemannan
Akkermansia muciniphila
Alchornea
Algae
algal oil
Aloe vera
Amor seco
anamu
andrographolide
anemarrhena asphodeloides
anthocyanins
apigenin
apple
apple cider vinegar
astaxanthin
Asteraceae
astragalin
Baccharoides anthelmintica
Bacillus
bacillus clausii
bacillus coagulans
bacillus subtilis
bacteria
bael
barberry
Basidiomycota
beta caryophyllene
Bifidobacteria
Bifidobacterium
Bifidobacterium adolescentis
Bifidobacterium animalis
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium longum
bilberry
bio ecolian (proprietary)
black nightshade
blackboard tree
blueberry
Boswellia
Boswellic Acid
bromelain
buckthorn
butyrate triglyceride
butyric acid
cabbage
cactus
cat's claw
Chinese salvia root
chlorella
Clostridium butyricum
colocynth
Coptis chinensis
cowage seed
Curcuma
curcumen
curcumin
Curcuminoid
diterpenes
Euphorbia
fiber
fiber blend (proprietary)
flavonols
Frangula
fucoidan
gallic acid
garlic bulb
ginger
Glycomacropeptides
Glycyrrhetinic acid
green tea
Guava
Hedyotis
Helicteres isora
hemp oil
hericium mushroom
Humic acid
immunoglobin G
Immunoglobulin G
inulin
isomalto-oligosaccharide
Kefir
L-glutamine
L. lactis
lactiplantibacillus plantarum
Lactobacillus
Lactobacillus acidophilus
Lactobacillus brevis
Lactobacillus bulgaricus
Lactobacillus casei
Lactobacillus delbrueckii
Lactobacillus fermentum
Lactobacillus gasseri
Lactobacillus johnsonii
Lactobacillus kefiri
Lactobacillus lactis
Lactobacillus paracasei
Lactobacillus pentosus
Lactobacillus plantarum
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactobacillus sakei
Lactobacillus salivarius
Lactococcus casei
Lactococcus lactis
Lactococcus rhamnosus
Lactoferrin
licorice root
Mucilage
N-acetyl-cysteine (NAC)
Nimbidin
Oligosaccharides
Osthole
Oxymatrine
Patrinia
Pediococcus acidilactici
Peptides
phlorotannins
picrorhiza kurroa
Plantago
plantain
polysaccharides
pomegranate
prebiotic blend (proprietary)
probiotics
Propionibacterium freudenreichii
quercetin
resveratrol
Rhus coriaria
rosmarinic acid
Saccharomyces boulardii
Scabrous Gentian
Slippery Elm
slippery elm bark
specialized pro-resolving mediators (SPMs)
spirulina
streptococcus thermophilus
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Products containing Bacillus

We currently have no products on Vitabase that contain this ingredient.