Evidence supporting the use of: Blueberry
For the health condition: Colitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Blueberry (Vaccinium spp.) has garnered scientific interest for its potential role in supporting colitis, particularly due to its high content of polyphenols, especially anthocyanins. Several preclinical studies have demonstrated that blueberry supplementation can ameliorate symptoms of colitis in animal models. For example, research published in PLoS One (2017) and Journal of Nutritional Biochemistry (2015) found that blueberry extracts reduced inflammation, oxidative stress, and histological damage in chemically-induced colitis in mice. The mechanisms are believed to involve modulation of inflammatory cytokines (such as TNF-α, IL-6), enhancement of antioxidant enzyme activity, and beneficial shifts in gut microbiota composition.

Human evidence is more limited, but a small pilot study (Nutrition Research, 2019) indicated that a blueberry-enriched diet was well tolerated in patients with mild ulcerative colitis and suggested potential benefits on inflammation markers and gut microbiome diversity. However, data from large-scale, randomized controlled trials are lacking, and thus, the evidence is not robust enough for clinical recommendations. The use of blueberry for colitis is not rooted in traditional medicine, but in emerging nutritional and biomedical research.

In summary, while promising preclinical data exist and preliminary human studies are encouraging, more rigorous clinical trials are needed. The current level of scientific support for blueberry in colitis can be rated as moderate (3 out of 5), indicating some evidence but insufficient for definitive clinical endorsement.

More about blueberry
More about Colitis

Other ingredients used for Colitis

Akkermansia muciniphila
algal oil
Aloe vera
anthocyanins
apple
astaxanthin
bacillus clausii
bacillus coagulans
bacillus subtilis
barberry
beta caryophyllene
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium longum
bilberry
bio ecolian (proprietary)
blueberry
bromelain
butyrate triglyceride
cat's claw
Chinese salvia root
chlorella
Coptis chinensis
cowage seed
turmeric
curcumin
fiber blend (proprietary)
flavonols
garlic bulb
ginger
green tea
hemp oil
immunoglobin G
inulin
isomalto-oligosaccharide
L-glutamine
Lactobacillus acidophilus
Lactobacillus brevis
Lactobacillus bulgaricus
Lactobacillus casei
Lactobacillus fermentum
Lactobacillus gasseri
Lactobacillus lactis
Lactobacillus paracasei
lactiplantibacillus plantarum
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactobacillus salivarius
Lactococcus lactis
Lactoferrin
licorice root
N-acetyl-cysteine (NAC)
plantain
pomegranate
prebiotic blend (proprietary)
butyric acid
quercetin
resveratrol
Saccharomyces boulardii
slippery elm bark
specialized pro-resolving mediators (SPMs)
spirulina
streptococcus thermophilus
tributyrin
Triphala
Zinc
xanthium (cockleburs)
blackboard tree
picrorhiza kurroa
Swertia
buckthorn
anemarrhena asphodeloides
Algae
apple cider vinegar
apigenin
anamu
Alchornea
andrographolide
Asteraceae
Acemannan
Amor seco
astragalin
Bifidobacterium
Bifidobacterium adolescentis
Boswellic Acid
bael
Basidiomycota
Boswellia
Baccharoides anthelmintica
Bifidobacterium animalis
back nightshade
bacteria
Bifidobacteria
Bacillus
cactus
Curcuminoid
curcumen
Curcuma
cabbage
Clostridium butyricum
colocynth
diterpenes
Euphorbia
fucoidan
fiber
Frangula
gallic acid
Glycomacropeptides
Guava
Glycyrrhetinic acid
Hedyotis
Helicteres isora
Humic acid
hericium mushroom
Immunoglobulin G
Kefir
Lactobacillus plantarum
Lactobacillus pentosus
Lactobacillus sakei
Lactobacillus kefiri
Lactococcus rhamnosus
Lactococcus casei
Lactobacillus delbrueckii
Lactobacillus johnsonii
Lactobacillus
L. lactis
Mucilage
Nimbidin
Oligosaccharides
Oxymatrine
Osthole
polysaccharides
Plantago
phlorotannins
Propionibacterium freudenreichii
probiotics
Pediococcus acidilactici
Patrinia
Peptides
rosmarinic acid
Rhus coriaria
reed herb
Slippery Elm
Scabrous Gentian
Triterpenes
Tayuya
Trametes
Varuna

Products containing blueberry

Pure Encapsulations Açai 600
Pure Encapsulations CogniMag
Pure Encapsulations CurcumaSorb Mind
Designs For Health EssentiaGreens™
Douglas Laboratories Juvenon Pro Cognitive
Klean Athlete Klean Focus®
Klean Athlete Klean Multivitamin ™
Vitabase Life's Essentials Plus
Douglas Laboratories Liquid Multivitamin
Metagenics MetaKids Multi Soft Chew Grape
Douglas Laboratories Optimized Curcumin With Neurophenol™
Thorne Ovarian Care
Designs For Health PaleoGreens®
Designs For Health PaleoGreens®
Designs For Health PaleoReds®
Designs For Health PhytoBiome™
Metagenics PhytoGanix® Tropical Fruit
Metagenics PhytoMulti™ Multivitamin
Metagenics PhytoMulti With Iron
Metagenics PhytoMulti Without Iron
Metagenics PhytoMultivitamin
Pure Encapsulations Poly-Prebiotic Powder
Pure Encapsulations Polyphenol Nutrients
Pure Encapsulations Polyphenol Nutrients
Designs For Health Primal Multi™
Pure Encapsulations PS Plus
Pure Encapsulations PureLean® Protein
Pure Encapsulations RevitalAge™ Ultra
Douglas Laboratories Ultra Preventive
Douglas Laboratories Ultra Preventive
Douglas Laboratories Ultra Preventive ® 2 Daily
Douglas Laboratories Ultra Preventive ®-EZ Swallow
Douglas Laboratories Ultra Preventive® X
Douglas Laboratories Ultra Protein Green
Metagenics UltraMeal® Daily Support Dutch Chocolate
Metagenics UltraMeal Daily Support Mixed Berry
Metagenics Wellness Essentials Active Daily Packs
Metagenics Wellness Essentials Brain Health Daily Packs
Metagenics Wellness Essentials® Daily Packs
Metagenics Wellness Essentials Healthy Balance Daily Packs
Metagenics Wellness Essentials Men's Vitality Daily Packs
Metagenics Wellness Essentials Women's Daily Packs
Metagenics Wellness Essentials Women's Prime Daily Packs