Evidence supporting the use of: Curcuminoid
For the health condition: Colitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Curcuminoids, the active polyphenolic compounds found in turmeric (Curcuma longa), have been investigated for their potential benefits in treating colitis, particularly inflammatory bowel diseases (IBD) such as ulcerative colitis. There is a moderate level of scientific evidence supporting their use in this context. Multiple preclinical studies have demonstrated that curcuminoids possess potent anti-inflammatory properties, inhibiting pathways such as NF-κB and reducing the production of pro-inflammatory cytokines. These mechanisms are relevant to the pathophysiology of colitis, which is characterized by chronic intestinal inflammation.

A number of small to moderate-sized randomized controlled trials (RCTs) in humans suggest curcuminoids may help maintain remission in ulcerative colitis. For example, a 2006 double-blind, placebo-controlled trial (Hanai et al., Clinical Gastroenterology and Hepatology) found that patients receiving curcumin in addition to standard therapy had significantly lower relapse rates compared to placebo. Meta-analyses and systematic reviews (e.g., Ng et al., Journal of Crohn's and Colitis, 2013) generally conclude that curcumin is a promising adjunctive therapy for ulcerative colitis but call for larger and longer-duration studies to confirm efficacy and safety.

Overall, while the evidence base is not as robust as for some conventional therapies, curcuminoids are supported by a combination of mechanistic rationale, preclinical data, and emerging clinical trial evidence. However, their use should be considered as adjunctive rather than primary therapy, and patients should consult healthcare providers before using them for colitis.

More about Curcuminoid
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Acemannan
Akkermansia muciniphila
Alchornea
Algae
algal oil
Aloe vera
Amor seco
anamu
andrographolide
anemarrhena asphodeloides
anthocyanins
apigenin
apple
apple cider vinegar
astaxanthin
Asteraceae
astragalin
Baccharoides anthelmintica
Bacillus
bacillus clausii
bacillus coagulans
bacillus subtilis
bacteria
bael
barberry
Basidiomycota
beta caryophyllene
Bifidobacteria
Bifidobacterium
Bifidobacterium adolescentis
Bifidobacterium animalis
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium longum
bilberry
bio ecolian (proprietary)
black nightshade
blackboard tree
blueberry
Boswellia
Boswellic Acid
bromelain
buckthorn
butyrate triglyceride
butyric acid
cabbage
cactus
cat's claw
Chinese salvia root
chlorella
Clostridium butyricum
colocynth
Coptis chinensis
cowage seed
Curcuma
curcumen
curcumin
Curcuminoid
diterpenes
Euphorbia
fiber
fiber blend (proprietary)
flavonols
Frangula
fucoidan
gallic acid
garlic bulb
ginger
Glycomacropeptides
Glycyrrhetinic acid
green tea
Guava
Hedyotis
Helicteres isora
hemp oil
hericium mushroom
Humic acid
immunoglobin G
Immunoglobulin G
inulin
isomalto-oligosaccharide
Kefir
L-glutamine
L. lactis
lactiplantibacillus plantarum
Lactobacillus
Lactobacillus acidophilus
Lactobacillus brevis
Lactobacillus bulgaricus
Lactobacillus casei
Lactobacillus delbrueckii
Lactobacillus fermentum
Lactobacillus gasseri
Lactobacillus johnsonii
Lactobacillus kefiri
Lactobacillus lactis
Lactobacillus paracasei
Lactobacillus pentosus
Lactobacillus plantarum
Lactobacillus reuteri
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Lactobacillus sakei
Lactobacillus salivarius
Lactococcus casei
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licorice root
Mucilage
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Nimbidin
Oligosaccharides
Osthole
Oxymatrine
Patrinia
Pediococcus acidilactici
Peptides
phlorotannins
picrorhiza kurroa
Plantago
plantain
polysaccharides
pomegranate
prebiotic blend (proprietary)
probiotics
Propionibacterium freudenreichii
quercetin
resveratrol
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rosmarinic acid
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spirulina
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Products containing Curcuminoid

We currently have no products on Vitabase that contain this ingredient.