Evidence supporting the use of: Immunoglobulin G
For the health condition: Colitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Immunoglobulin G (IgG) has some scientific basis for use in the treatment of colitis, particularly in certain clinical contexts. IgG is the most abundant type of antibody in the blood and is critical for immune defense. In the context of colitis—especially severe or refractory cases of ulcerative colitis or Crohn’s disease—intravenous immunoglobulin (IVIG), which is a pooled preparation of IgG from multiple donors, has been investigated as a treatment option. The rationale is that IVIG can modulate immune responses, decrease inflammation, and neutralize pathogenic autoantibodies or microbial toxins that may contribute to colitis. Clinical evidence, however, is limited and mostly consists of case reports, small case series, and a few uncontrolled studies. Some reports indicate that IVIG can induce remission in patients with steroid-refractory or treatment-resistant inflammatory bowel disease (IBD), including colitis. However, larger randomized controlled trials are lacking, and current guidelines do not recommend IVIG as a standard therapy for colitis due to insufficient high-quality evidence. Oral IgG preparations (such as serum-derived bovine immunoglobulin) have also been explored in some studies, showing potential benefits by binding and neutralizing microbial antigens and toxins in the gut. Some small trials and observational studies suggest possible improvement in symptoms, but again, the evidence is not robust. In summary, while there is a scientific rationale and some clinical experience supporting the use of IgG for colitis, the overall evidence is weak and not definitive, meriting a low-to-moderate evidence rating.

More about Immunoglobulin G
More about Colitis

Other ingredients used for Colitis

akkermansia muciniphila
algal oil
aloe vera
anthocyanins
apple
astaxanthin
bacillus clausii
bacillus coagulans
bacillus subtilis
barberry
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
bilberry
bio ecolian (proprietary)
blueberry
bromelain
butyrate triglyceride
cat's claw
Chinese salvia root
chlorella
Coptis chinensis
cowage seed
turmeric
curcumin
fiber blend (proprietary)
flavonols
garlic bulb
ginger
green tea
hemp oil
immunoglobin G
inulin
isomalto-oligosaccharide
l-glutamine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus casei
lactobacillus fermentum
lactobacillus gasseri
lactobacillus lactis
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
lactoferrin
licorice root
n-acetyl-cysteine (NAC)
plantain
pomegranate
prebiotic blend (proprietary)
butyric acid
quercetin
resveratrol
saccharomyces boulardii
slippery elm bark
specialized pro-resolving mediators (SPMs)
spirulina
streptococcus thermophilus
tributyrin
triphala
zinc
xanthium (cockleburs)
blackboard tree
picrorhiza kurroa
swertia
buckthorn
anemarrhena asphodeloides
algae
Apple Cider Vinegar
Apigenin
Anamu
Alchornea
Andrographolide
Asteracea
Acemannan
Amor seco
Astragalin
Bifidobacterium
Bifidobacterium adolescentis
Boswellic Acid
Bael
Basidiomycota
Boswellia
Baccharoides anthelmintica
Bifidobacterium animalis
Black Nightshade
Bacteria
Bifidobacteria
Bacillus
Cactus
Curcuminoid
Curcumen
Curcuma
Cabbage
Clostridium butyricum
Colocynth
Diterpenes
Euphorbia
Fiber

Products containing Immunoglobulin G

We currently have no products on Vitabase that contain this ingredient.