Synopsis

Source of validity: Scientific
Rating (out of 5): 2

L-glutamine is an amino acid that serves as a fuel source for enterocytes (intestinal cells) and plays a role in maintaining gut barrier function and modulating inflammation. Its use in colitis, particularly inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn’s disease, is supported by some preclinical and clinical research, though evidence is not robust or universally conclusive. Animal studies frequently show that glutamine supplementation can reduce intestinal inflammation, enhance mucosal healing, and improve gut integrity. In humans, results are mixed: several small clinical trials and pilot studies have investigated oral or enteral glutamine supplementation in patients with colitis or IBD, with some reporting improvements in mucosal repair and symptoms, while others found no significant benefit compared to placebo. Systematic reviews suggest that while glutamine appears safe and may have potential as an adjunctive therapy, larger and more rigorous randomized controlled trials are needed to establish efficacy. Most clinical guidelines do not currently recommend glutamine as a standard treatment for colitis due to insufficient evidence. Thus, while there is a plausible scientific rationale and some preliminary validation, the clinical evidence supporting its use remains limited.

More about L-glutamine
More about Colitis

Other ingredients used for Colitis

Other health conditions supported by L-glutamine

Products containing L-glutamine

Douglas Laboratories 5-HTP Plus Formula
Designs For Health Amino-D-Tox™
Designs For Health Amino-D-Tox™
Pure Encapsulations Amino-NR
Pure Encapsulations Amino Replete
Designs For Health BCAA Powder with L-Glutamine
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Berry
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus pH
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Vanilla
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Berry
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus pH Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Chai
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Vanilla
Integrative Therapeutics Detoxication Factors
Integrative Therapeutics Detoxication Factors
Thorne EnteroMend NSF
Pure Encapsulations EpiIntegrity
Pure Encapsulations G.I. Fortify
Pure Encapsulations G.I. Fortify
Pure Encapsulations G.I. Integrity
Pure Encapsulations G.I. Integrity
Designs For Health GI Revive®
Designs For Health GI Revive®
Metagenics GI Sustain™ Powder
Metagenics Glutagenics® powder
Integrative Therapeutics Glutamine Forte Drink Mix
Vitabase HGH Complex
Designs For Health IBSynergy™
Klean Athlete Klean Essential Aminos + HMB®
Klean Athlete Klean Isolate ™
Thorne L-Glutamine
Pure Encapsulations l-Glutamine
Designs For Health L-Glutamine
Douglas Laboratories L-Glutamine
Pure Encapsulations l-Glutamine 500 mg
Pure Encapsulations l-Glutamine 850 mg
Pure Encapsulations l-Glutamine 850 mg
Designs For Health L-Glutamine Powder
Designs For Health L-Glutamine Powder
Douglas Laboratories L-Glutamine Powder
Thorne L-Glutamine Powder NSF
Pure Encapsulations Liver G.I. Detox
Thorne MediClear Plus
Integrative Therapeutics Multiplex-1 No-Iron
Douglas Laboratories Muscle Protect™ with HMB®
Designs For Health Neurolink™
Integrative Therapeutics Nutrivitamin No-Iron
Pure Encapsulations PureBi•Ome™ G.I.
Metagenics Ultra Potent-C 1000
Metagenics Ultra Potent-C Chewable
Metagenics UltraClear Plus® Detox Powder
Metagenics UltraClear Plus Detox Powder Berry
Metagenics UltraClear Plus Detox Powder Pineapple/Banana
Metagenics UltraClear Plus pH Detox Powder Pineapple/Banana
Metagenics UltraClear Plus pH Detox Powder Vanilla
Metagenics UltraClear RENEW Detox Powder Berry
Metagenics UltraClear RENEW Detox Powder Chai
Metagenics UltraClear RENEW Detox Powder Vanilla
Pure Encapsulations UltraDetox 10-Day Pure Pack
Metagenics UltraGI Replenish® Chocolate
Metagenics UltraGI Replenish Chocolate
Metagenics UltraGI Replenish Vanilla
Metagenics UltraGI Replenish Vanilla
Metagenics UltraInflamX Plus 360°® Chocolate/Orange
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Orange
Metagenics UltraInflamX Plus 360° Original Spice
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraInflamX Plus 360° Pineapple/Banana