Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus lactis (more accurately referred to as Lactococcus lactis) is a lactic acid bacterium commonly used in the dairy industry for fermentation. While it is not among the most extensively studied probiotics for colitis (such as Lactobacillus rhamnosus GG or Escherichia coli Nissle 1917), there is some emerging scientific evidence suggesting its potential benefits in supporting or treating colitis, particularly in animal models.

Experimental studies have demonstrated that administration of L. lactis can modulate the gut immune response, reduce the production of pro-inflammatory cytokines, and enhance mucosal barrier function. For example, mouse models of colitis treated with L. lactis showed reduced signs of inflammation and improved histological outcomes. Some genetically engineered strains of L. lactis that secrete anti-inflammatory molecules, such as interleukin-10, have shown even greater efficacy in reducing colitis symptoms in preclinical settings.

However, clinical data in humans are limited. Few trials have investigated L. lactis in patients with inflammatory bowel diseases, and the results are not yet sufficient to draw strong conclusions. The main body of supporting evidence is thus preclinical, not clinical. Because of this, the evidence rating is moderate to low (2 out of 5). Further research, including well-designed human clinical trials, is needed to confirm the efficacy and safety of L. lactis for colitis.

More about Lactobacillus lactis
More about Colitis

Other ingredients used for Colitis

Other health conditions supported by Lactobacillus lactis

Products containing Lactobacillus lactis