Evidence supporting the use of: Peptides (unspecified)
For the health condition: Colitis
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Peptides, particularly bioactive peptides derived from dietary proteins, have been investigated for their potential role in supporting or treating colitis, including inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn's disease. Preclinical studies, especially in animal models, have demonstrated that certain peptides can exert anti-inflammatory, immunomodulatory, and barrier-protective effects on the gut. For example, peptide fragments from milk proteins (e.g., casein and whey) and fish proteins have shown potential to decrease pro-inflammatory cytokine production, enhance mucosal healing, and modulate gut microbiota in rodent models of colitis. Additionally, there is scientific rationale for the use of peptide-based enteral nutrition formulas (also called "elemental" or "semi-elemental" diets) in clinical settings; these formulas contain partially hydrolyzed proteins (peptides) and have been shown to induce remission in some patients with active Crohn's disease, especially in pediatric populations.
However, high-quality clinical trials specifically testing isolated peptides for colitis management in humans are limited. The bulk of evidence comes from animal research and from clinical studies on peptide-based nutritional support rather than purified peptides as therapeutic agents. As a result, while there is scientific interest and preclinical evidence supporting the use of certain peptides in colitis, the clinical evidence remains moderate, justifying a rating of 3 out of 5.
Other ingredients used for Colitis
akkermansia muciniphilaalgal oil
aloe vera
anthocyanins
apple
astaxanthin
bacillus clausii
bacillus coagulans
bacillus subtilis
barberry
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
bilberry
bio ecolian (proprietary)
blueberry
bromelain
butyrate triglyceride
cat's claw
Chinese salvia root
chlorella
Coptis chinensis
cowage seed
turmeric
curcumin
fiber blend (proprietary)
flavonols
garlic bulb
ginger
green tea
hemp oil
immunoglobin G
inulin
isomalto-oligosaccharide
l-glutamine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus casei
lactobacillus fermentum
lactobacillus gasseri
lactobacillus lactis
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
lactoferrin
licorice root
n-acetyl-cysteine (NAC)
plantain
pomegranate
prebiotic blend (proprietary)
butyric acid
quercetin
resveratrol
saccharomyces boulardii
slippery elm bark
specialized pro-resolving mediators (SPMs)
spirulina
streptococcus thermophilus
tributyrin
triphala
zinc
xanthium (cockleburs)
blackboard tree
picrorhiza kurroa
swertia
buckthorn
anemarrhena asphodeloides
algae
Apple Cider Vinegar
Apigenin
Anamu
Alchornea
Andrographolide
Asteracea
Acemannan
Amor seco
Astragalin
Bifidobacterium
Bifidobacterium adolescentis
Boswellic Acid
Bael
Basidiomycota
Boswellia
Baccharoides anthelmintica
Bifidobacterium animalis
Black Nightshade
Bacteria
Bifidobacteria
Bacillus
Cactus
Curcuminoid
Curcumen
Curcuma
Cabbage
Clostridium butyricum
Colocynth
Diterpenes
Euphorbia
Fiber
Other health conditions supported by peptides (unspecified)
ArthritisAthletic and Exercise Aids
Body Building
Broken Bones
Cartilage Damage
Chemotherapy (reducing side effects)
Colitis
Crohn's Disease
Exercise
Fibrosis
Hair (loss or thinning)